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董常明

  

1、基本信息
姓名:董常明
职称:教授
电话:021-54748916 
邮箱:cmdong@sjtu.edu.cn
主页:scce.sjtu.edu.cn
通讯地址:上海市东川路800号化学化工学院B418

2、教育经历
1995-1998  武汉大学 化学系 硕士
1998-2001  北京大学 化学与分子工程学院 博士
2002-2003  美国Emory Univ 医学院 博士后

3、工作经历
2004-2008  上海交通大学 化学化工学院 讲师、副教授、硕士生导师、课题组长

2009-至今  上海交通大学 化学化工学院 教授、博士生导师、课题组长

4、研究方向
1)高分子生物材料(生物降解高分子、聚乳酸、聚己内酯、脂肪族聚酯)

2)生物高分子(聚氨基酸或聚肽、糖聚合物、天然多糖、糖蛋白缀合物)

3智能高分子与拓扑结构高分子(刺激响应高分子、拓扑结构控制)

4)纳米生物材料与纳米医学(响应性纳米医学、光热治疗、诊断治疗剂)
(5)药物控释体系与组织工程(靶向药物释放、超分子或可注射水凝胶)

5、科研项目
主持和完成国家自然科学基金面上(青年)项目(6项)、上海市重大基础研究项目、教育部新世纪人才基金、教育部留学回国人员基金、交大晨星学者基金等多项课题研究。

6、荣誉奖励
12008年教育部新世纪优秀人才支持计划

22008年上海交通大学晨星青年学者奖励计划

32011年、2012年获上海市优秀硕士论文导师(学生:华崇硕士和陈怡硕士)

(4)2012年上海交通大学晨星青年学者A类计划。

7、教学工作

(1)本科生课程:功能高分子(05年~)、生物医药大分子(06年)、高分子科学进展(13年)

2)硕士生课程:有机功能材料(05年~,全日制硕士与工程硕士)

3)博士生课程:材料科学前沿专题(04年~)

8、代表性论文及专著

61.Pan Li and Chang-Ming Dong*Phototriggered Ring-Opening Polymerization of a Photocaged LLysine NCarboxyanhydride to Synthesize Hyperbranched and Linear Polypeptides,ACS Macro Lett. 2017, 6, 292-297.

60.Yuanfeng Gao and Chang-Ming Dong*,Reduction- and thermo-sensitive core-crosslinked polypeptide hybrid micelles for triggered and intracellular drug release,Polym. Chem. 2017,8, 1223-1232.
59. Wu Xingjie, Zhou Linzhu, Su Yue, Dong Chang-Ming*, Plasmonic, Targeted,and Dual Drugs-Loaded Polypeptide Composite Nanoparticles for Synergistic Cocktail Chemotherapy with Photothermal Therapy, Biomacromolecules, 2016, 17,2489-2501.

58. Wu Xingjie, Zhou Linzhu, Su Yue, Dong Chang-Ming*, A polypeptide micelle template method to prepare polydopamine composite nanoparticles for synergistic photothermal–chemotherapy, Polym. Chem., 2016, 7, 5552–5562.
57.Wu Xingjie, Zhou Linzhu, Su Yue, Dong Chang-Ming*, An autoreduction method to prepare plasmonic gold-embedded polypeptide micelles for synergistic chemo-photothermal therapy, J. Mater. Chem. B, 2016, 4, 2142–2152.
56.Liu Gang, Liu Na, Zhou Linzhu, Su Yue, Dong Chang-Ming*, NIR-responsive polypeptide copolymer upconversion composite nanoparticles for triggered drug release and enhanced cytotoxicity, Polym. Chem., 2015, 6, 4030–4039.
55.Wu Xingjie, Zhou Linzhu, Su Yue, Dong Chang-Ming*, Comb-like
poly(L-cysteine) derivatives with different side groups: synthesis via photochemistry and click chemistry, multi-responsive nanostructures, triggered drug release and cytotoxicity,
Polym. Chem., 2015, 6, 6857–6869.
54.Gao Yanqin, Wu Xingjie, Zhou Linzhu, Su Yue, Dong Chang-Ming*, A Sweet Polydopamine Nanoplatform for Synergistic Combination of Targeted Chemo-Photothermal Therapy, Macromolecular Rapid Communications, 2015, 36,916–922.
53.Wu Xingjie, Gao Yanqin, Dong Chang-Ming*, Polymer/gold hybrid nanoparticles: from synthesis to cancer theranostic applications, RSC Advances, 2015,5, 13787–13796.

52. Gang Liu, Linzhu Zhou, Yue Su and Chang-Ming Dong*,An NIR-responsive and sugar-targeted polypeptide composite nanomedicine for intracellular cancer therapy, Chem Comm 2014,50,12538-12541.

51. Gang Liu , Linzhu Zhou , Yanfei Guan , Yue Su , Chang-Ming Dong *, Multi-Responsive Polypeptidosome: Characterization, Morphology Transformation,and Triggered Drug Delivery, Macromol. Rapid Commun. 2014, 35,1673-1678.

50. Xiao Chang, Lisha Liu, Yanfei Guan, Chang-Ming Dong*, Disulfide-Centered Star-Shaped Polypeptide-PEO Block Copolymers for Reduction-Triggered Drug Release, J. Polym. Sci., Part A: Polym. Chem. 2014, 52, 2000-2010. 

49. Lin Sun, Bangshang Zhu, Yue Su and Chang-Ming Dong*,
Light-responsive linear-dendritic amphiphiles and their nanomedicines for NIR-triggered drug release, Polym. Chem., 2014, 5, 1605-1613.

48. Xiao Chang, Chang-Ming Dong*,"Synthesis of Hyperbranched Polypeptide and PEO Block Copolymer by Consecutive Thiol-Yne Chemistry", Biomacromolecules 2013, 14, 33293337.

47. Gang Liu, Wei Liu, Chang-Ming Dong*,  UV- and NIR-Responsive Polymeric Nanomedicines for On-Demand Drug Delivery, Polym. Chem., 2013, 4,3431-3443(Invited review).

46. Dong-Lin Liu, Xiao Chang, Chang-Ming Dong*, Reduction- and thermo-sensitive star polypeptide micelles and hydrogels for on-demand drug delivery, Chem Comm 2013, 49, 1229-1231.

45. Chang-Ming Dong*, Gang Liu, Linear-Dendritic Biodegradable Block Copolymers: From Synthesis To Application In Bionanotechnology, Polym. Chem., 2013, 4, 46-52 (Invited Minireview, 6# of Top 10 Most Read article in Septemper, 2012).

44. Lin Sun,Xiaofei Ma, Chang-Ming Dong*, Bangshang Zhu*,  Xinyuan Zhu, 'NIR-Responsive and Lectin-Binding Doxorubicin-Loaded Nanomedicine from Janus-Type Dendritic PAMAM Amphiphiles', Biomacromolecules, 2012, 13, 3581-3591. (Most Read Articles: 6# of Top 20 in October 2012)

43. Gang Liu, Chang-Ming Dong*, "Photoresponsive Poly(S-(o-nitrobenzyl)-L-cysteine)-b-PEO from a LCysteine N-Carboxyanhydride Monomer: Synthesis, Self-Assembly, and Phototriggered Drug Release", Biomacromolecules, 2012, 13, 1573-1583. (Most Read Articles: Top 20 in April-May 2012)

42. Ye Liao, Chang-Ming Dong*, "Synthesis, Conformation Transition, Liquid Crystal Phase, and Self-Assembled Morphology of Thermosensitive Homopolypeptide",J Polym Sci Part A: Polym Chem 2012,50,18341843.

41.Yu-Jing Wang, Chang-Ming Dong*, "Bioreducible and Core-Crosslinked Hybrid Micelles from Trimethoxysilyl-Ended Poly(e-caprolactone)-S-S-Poly(ethylene oxide) Block Copolymers: Thiol-Ene Click Synthesis and Properties", J Polym Sci Part A: Polym Chem 2012,50,16451656.

40. You-Cui Xu, Chang-Ming Dong*, "Dendron-Like Poly(e-benzyloxycarbonyl-L-lysine)/Linear PEO Block Copolymers: Synthesis, Physical Characterization, Self-Assembly, and Drug-Release Behavior", J Polym Sci Part A: Polym Chem 2012, 50,12161225.

39. Lin Sun, Wei Liu, Chang-Ming Dong*, "Bioreducible Micelles and Hydrogels with Tunable Properties from Multi-Armed Biodegradable Copolymer", Chem Comm 2011, 47,11282-11284.

38. Lin Sun, Yang Yang, Chang-Ming Dong*, Yen Wei, "Two-Photon-Sensitive and Sugar-Targeted Nanocarriers from Degradable and Dendritic Amphiphiles", Small 2011, 7, 401-406.

37. Wei Liu, Chang-Ming Dong*, "Versatile Synthesis of Asymmetrical Dendron-Like/Dendron-Like Poly(Caprolactone)-b-Poly(Benzyl-L-Glutamate) Block Copolymers", J. Polym. Sci. Polym. Chem. 2011, 49, 3491-3498.

36. Wei Liu, Chang-Ming Dong*, Versatile Strategy for the Synthesis of Hyperbranched Poly(e-caprolactone)s and Polypseudorotaxanes Thereof", Macromolecules 2010, 43, 8447-8455.

35. Lin Sun, Lin-Jing Shen, Ming-Qiang Zhu, Chang-Ming Dong*, Yen Wei, Synthesis, Self-Assembly, Drug-Release Behavior, and Cytotoxicity of Triblock and Pentablock Copolymers Composed of Poly(e-caprolactone),Poly(L-lactide), and Poly(ethylene glycol), J Polym Sci Polym Chem 2010, 48, 4583-4593.

34. Yi Chen, Xiao-Hui Pang, Chang-Ming Dong*, Dual Stimuli-Responsive Supramolecular Polypeptide-Based Hydrogel and Reverse Micellar Hydrogel Mediated by Host-Guest Chemistry, Adv Funct Mater 2010, 20, 579-586.

33. Yi Chen, Chang-Ming Dong*, "pH-Sensitive Supramolecular Polypeptide-Based Micelles and Reverse Micelles Mediated by Hydrogen-Bonding Interactions or Host-Guest Chemistry: Characterization and In Vitro Controlled Drug Release", J. Phys. Chem. B 2010, 114, 74617468.

32. Yuan You, Yi Chen, Chong Hua, Chang-Ming Dong*, Synthesis and Thermoreversible Gelation of Dendron-like Polypeptide/Linear Poly(e-caprolactone)/Dendron-like Polypeptide Triblock Copolymers, J Polym Sci Polym Chem 2010, 48, 709-718.

31. Yang Yang, Chong Hua, Chang-Ming Dong*, Synthesis, Self-Assembly, and In Vitro Doxorubicin Release Behavior of Dendron-like/Linear/Dendron-like Poly(ε-caprolactone)-b-Poly(ethylene glycol)-b-Poly(ε-caprolactone) Triblock Copolymers, Biomacromolecules 2009, 10, 2310-2318.

30. Chong Hua, Chang-Ming Dong*, Yen Wei, " Versatile Strategy for the Synthesis of Dendron-like Polypeptide/Linear Pol(caprolactone) Block Copolymers via Click Chemistry", Biomacromolecules 2009, 10,1140-1148.
29. Qing Liu, Chen Cai, Chang-Ming Dong*, "Poly(L-lactide)-b-poly(ethylene oxide) copolymers with different arms: Hydrophilicity, biodegradable nanoparticles, in vitro degradation, and drug-release behavior", J Biomed Mater Res 2009, 88A, 990999.
28. Xiao-Hui Dai, Hua-Dong Zhang, Chang-Ming Dong*, Fabrication, biomolecular binding, in vitro drug release behavior of sugar-installed nanoparticles from star poly(ε-caprolactone)/glycopolymer biohybrid with a dendrimer core, Polymer 2009, 50, 4626-4634.
27. Shuo Qiu, Hui Huang, Xiao-Hui Dai, Wei Zhou, Chang-Ming Dong*, "Star-Shaped Polypeptide/Glycopolymer Biohybrids: Synthesis, Self-Assembly, Biomolecular Recognition, and Controlled Drug Release Behavior", J Polym Sci Polym Chem 2009, 47, 2009-2023.
26. Song-Ming Peng, Yi Chen, Chong Hua, Chang-Ming Dong*, "Dendron-like Polypeptide/Linear Poly(ethylene oxide) Biohybrids with Both Asymmetrical and Symmetrical Topologies Synthesized via the Combination of Click Chemistry and Ring-Opening Polymerization", Macromolecules 2009, 42,104-113.
25. Chong Hua, Song-Ming Peng, Chang-Ming Dong*, "Synthesis and Characterization of Linear-Dendron-like Poly(ε-caprolactone)-b-poly(ethylene oxide) Copolymers via the Combination of Ring-Opening Polymerization and Click Chemistry", Macromolecules 2008, 41,6686-6695.
24. Xiao-Hui Dai, Chang-Ming Dong*, D. Yan, "Supramolecular and Biomimetic Polypseudorotaxane/Glycopolymer Biohybrids: Synthesis, Glucose-Surfaced Nanoparticles, and Recognition with Lectin", J Phys Chem B 2008, 112, 3644-3652.
23.Wei Zhou, Xiao-Hui Dai, Chang-Ming Dong*, "Biodegradable and Biomimetic Polycaprolactone/Poly(lactobionamidoethylmethacrylate) Biohybrids: Synthesis, Lactose-Installed Nanoparticles and Recognition Properties", Macromol. Biosci. 2008, 8, 268-278.
22. Xiao-Hui Dai, Chang-Ming Dong*, "Synthesis, Self-Assembly and Recognition Properties of Biomimetic Star-Shaped Pol(caprolactone)-b-Glycopolymer Block Copolymers", J Polym Sci Polym Chem 2008, 46, 817-829.
21. Hao Feng, Chang-Ming Dong*, "Synthesis and characterization of phthaloyl-chitosan-g-poly(L-lactide) using an organic catalyst", Carbohydrate Polymers 2007, 70, 258264.
20. Chong Hua, Chang-Ming Dong*, "Synthesis, characterization, effect of architecture on crystallization of biodegradable poly(e-caprolactone)-b-poly(ethylene oxide) copolymers with different arms and nanoparticles thereof", J Biomed Mater Res 2007, 82A, 689700.
19. Xiao Hui Dai, Chang-Ming Dong*, et al. "Supramolecular Polypseudorotaxanes Composed of Star-Shaped Porphyrin-Cored Poly(E-caprolactone) and Cyclodextrin", Biomacromolecules 2006, 7, 3527-33.
18. Hao Feng, Chang-Ming Dong*, "Preparation, Characterization, and Self-Assembled Properties of Biodegradable Chitosan-Poly(L-lactide) Hybrid Amphiphiles", Biomacromolecules 2006, 7, 3069-75. (Most-Accessed Articles: October-December, 2006).
17. Hao Feng, Chang-Ming Dong*, "Preparation and Characterization of Chitosan-g-Poly(ε-caprolactone) Using an Organic Catalyst", J Polym Sci Polym Chem 2006, 44, 5353-61.
16. Jing Liang Wang, Chang-Ming Dong*, physical properties, crystallization kinetics, and spherulitic growth of well-defined poly(caprolactone)s with different arms", Polymer 2006, 47, 3218-3228.
15.Jing Liang Wang, Chang-Ming Dong*, Synthesis, Sequential Crystallization, and Morphological Evolution of Star-Shaped Poly(caprolactone)-b-Poly(L-lactide) Block Copolymer, Macromol Chem Phys 2006, 207,554-62.
14.Chen Cai, Lu, Wang, Chang-Ming Dong*, " Synthesis, Characterization, Effect of Architecture on Crystallization, and Spherulitic Growth of Poly(L-lactide)- b-Poly(ethylene oxide) Copolymers with Different Branch Arms, J Polym Sci Polym Chem 2006, 44, 2034-44.
13.Lu Wang, Chang-Ming Dong*, Synthesis, Crystallization Kinetics, and Spherulitic Growth of Linear and Star-Shaped Poly(L-lactide)s with Different Numbers of Arms, J Polym Sci Polym Chem 2006, 44, 2226-36.
12. Jing-Liang Wang, Lu Wang, Chang-Ming Dong*, "Synthesis, Crystallization and Morphology of Star-Shaped Poly(caprolactone)", J. Polym. Sci. Polym Chem. 2005,  43, 5449-5457.
11.Lu, Wang, Jing-Liang Wang, Chang-Ming Dong*, "Supramolecular inclusion complexes of star-shaped poly(-caprolactone) with -cyclodextrin", J. Polym. Sci. Polym Chem. 2005, 43, 4721-4730.
10.Chang-Ming Dong*, Y. Z. Guo, K.Y Qiu*, Z.W. Gu, X.-D. Feng; "In vitro degradation and controlled release behavior of d,l-PLGA50 and PCL-b-d,l-PLGA50 copolymer microspheres", J. Control. Rel. 2005, 107 (1), 53-64.
9.Chang-Ming Dong, X.Y. Wu, J. Caves, S.S. Rele, B.S. Thomas, E. L. Chaikof, "Photomediated crosslinking of C6-cinnamate derivatized type I collagen  ", Biomaterials 2005, 26, 4041-4049.
8.Chang-Ming Dong*, K M. Faucher,E.L. Chaikof, "Synthesis and Properties of Biomimetic Poly(L-glutamate)-b-Poly(2-acryloyloxyethyllactoside)-b-Poly(L-glutamate)Triblock Copolymers", J Polym Sci Polym Chem 2004, 42, 57545765.
7.Chang-Ming Dong, X.L.Sun, K. M. Faucher, R. Apkarian, E. L Chaikof, Synthesis and Characterization of Glycopolymer-Polypeptide Triblock Copolymers, Biomacromolecules, 2004, 5, 224-231.
6. S.J. Hou, X.L. Sun, Chang-Ming Dong, E. L. Chaikof, "Facile Synthesis of Chain-End Functionalized Glycopolymers for Site-Specific Bioconjugation", Bioconjugate Chem. 2004, 15, 954-959.
5. Chang-Ming Dong, Kun-Yuan Qiu, Zhong-Wei Gu, Xin-De Feng; Synthesis of Star-Shaped Poly(D,L-lactic acid-alt-glycolic acid)-b-Poly(L-Lactic Acid) with Multifunctional Initiator and SnOct2 Catalyst, J Polym Sci Polym Chem, 2002, 40, 409-415.
4. Chang-Ming Dong, Kun-Yuan Qiu, Zhong-Wei Gu, Xin-De Feng; Synthesis of Star-Shaped Poly(e-caprolactone)-b-(D,L-lactic acid-alt-glycolic acid) with Multifunctional Initiator and SnOct2 Catalyst, Macromolecules, 2001, 34, 4691-4696.
3. Chang-Ming Dong, Kun-Yuan Qiu, Zhong-Wei Gu, Xin-De Feng; Living Polymerization of D,L-3-Methylglycolide Initiated with Bimetallic (Al/Zn) m-oxo Alkoxide and Copolymers Thereof, J Polym Sci Polym Chem, 2001, 39(3), 357-367.
2. Chang-Ming Dong, Kun-Yuan Qiu, Zhong-Wei Gu, Xin-De Feng; Synthesis of Star-Shaped Poly(D,L-lactic acid-alt-glycolic acid) with Multifunctional Initiator and SnOct2 Catalyst, Polymer, 2001, 42, 6891-6896.
1. Chang-Ming Dong, Kun-Yuan Qiu, Zhong-Wei Gu, Xin-De Feng; Synthesis of Poly(D,L-lactic acid-alt-glycolic acid) from D,L-3-Methylglycolide, J Polym Sci Polym Chem, 2000, 38 (23), 4179-4184.

9、其它

欢迎对“生物高分子、生物材料、纳米医学”感兴趣的博士后、研究生、本科生加入!

招收入学申请制博士生、直博生、硕博生(C9高校、985高校、中科院、211研究生院高校等)。

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