题目：Exploring Chemical Orthogonality in Polymer Science: from Janus Beads to Sequence Controlled polymers
报告人：Prof. Filip Du Prez, Department of Organic and Macromolecular Chemistry, Ghent University, Belgium
时间：6月2日（周一），上午10:00
地点：化学B楼410会议室
邀请人：朱新远教授（化学化工学院）

报告摘要：

The continuous demand for nanostructured materials, devised for specific and high tech applications, undeniably challenges polymer chemists. Original synthetic strategies should encompass straightforward and widely applicable methodologies. Robust and efficient organic reactions, generally labeled as ‘click’ chemistry and originally developed for the synthesis of low-molecular-weight compounds, infiltrated the toolbox of synthetic macro- and supramolecular research groups during the last decade. Conjugation and modification reactions involving thiols have lately gained momentum as metal-free alternatives to the heavily exploited copper assisted azide–alkyne cyclo-addition [1,2]. In order to solve the thiol-related issues (smell, shelf life and synthetic availability) and to increase the functionality of the resulting products, one of our research interests consists of the exploration of the reactivity of a thiolactone as a latent thiol functionality: the thiol is released by aminolysis (ring-opening) of the thiolactone and can subsequently react with a thiol ‘scavenger’. Therefore, one part of the presentation will highlight the most important features of this approach, employed in various reactive systems for the exploration of novel ways toward functional nanostructured polymer materials (surfaces, particles, cyclic polymers, sequence controlled polymers) [3-6]. Secondly, a couple of straightforward approaches to obtain functionalized and nanostructured Janus-type particles will be discussed [7-9].
References: [1] Koo, S. P. S.; Stamenovic, M. M.; Prasath, R. A.; Inglis, A. J.; Du Prez, F. E.; Barner-Kowollik, C.; Camp, W. V.; Junkers, T. J. Polym. Sci., Part A: Polym. Chem. 2010, 48, 1699-1713. [2] Barner-Kowollik, C.; Du Prez, F. E.; Espeel, P.; Hawker, C. J.; Junkers, T.; Schlaad, H.; Van Camp, W. Angew. Chem., Int. Ed. 2011, 50, 60-62. [3] Espeel, P.; Goethals, F.; Du Prez, F. E. J. Am. Chem. Soc. 2011, 133(6), 1678-1681 [4] Espeel, P.; Goethals, F.; Stamenović, M.; Petton, L.; Du Prez, F. Polym. Chem., 2012, 3, 1007-1015 [5] P. Espeel, L. Carrette, K. Bury, S. Capenberghs, F. E. Du Prez, A. Madder, Angew. Chem. Int. Ed. 2013, 52, 1 – 5 [6] F. Goethals, S. Martens, P. Espeel, O. van den Berg, F. E. Du Prez, Macromolecules, 2014, 47, 61−69 [7] Gokmen, T.; Du Prez, F.; Porous Polymer Particles – A Comprehensive Guide to Synthesis, Characterization, Functionalization and Applications, Prog. Polym. Sci, 2012, 37, 365-405  [8] Gökmen, T.;  Brassinne, J.; Prasath, A.; Du Prez, F. Chem.Comm., 2011, 47, 4652–4654 [9] Kaufmann, T.; Gokmen, T.; Wendeln, C.; Schneiders, M.; Rinnen, S.; Arlinghaus, H.; Bon, S.; Du Prez, F. and Ravoo, B. Adv. Mat., 2011, 23, 79-83

报告人简介：

Prof. Filip Du Prez is since 1999 head of the Polymer Chemistry Research Group (www.PCR.UGent.be) at Ghent University in Belgium where 30 researchers are dealing with the design of functional polymer architectures and polymer materials, various types of (controlled) polymerization techniques and the development of new ‘click’ chemistries. A couple of actual research domains are sequence controlled polymers, polymers from renewable resources, polymeric capsules and microparticles, self-healing materials, high performance coatings and step growth polymerization in combination with ‘click’ chemistry. He is author of more than 175 peer-reviewed publications and patents (h-index 33), more than 10 book chapters and (co-)chairman of 10 (inter)national conferences on polymer chemistry related topics. In 2011 he co-edited a Wiley book on Complex Macromolecular Architectures. Since 2007 he is responsible for a large valorization consortium (Chemtech) in which two permanent business developers take care of the interface between the chemistry research at UGent and the chemical industry. In 2008, he had a Visiting Professor position at the CAMD Research Centre (UNSW, Sydney). In the same year, he became editor of the Elsevier-journal European Polymer Journal.