卢岩助理研究员
电子邮件：luyan92@sjtu.edu.cn
通讯地址：上海市东川路800号上海交通大学化学化工学院
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教育背景
2010-2014：四川大学化学学院，学士
2014-2019：四川大学化学学院，博士（导师：冯小明 院士）
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工作经历
2019-2021：美国得克萨斯大学奥斯汀分校（University of Texas at Austin），博士后（合作导师：Stephen F. Martin）
2022-至今 上海交通大学化学化工学院 助理研究员
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研究方向
1、金属有机化学与不对称催化
2、精细有机合成
3、可见光条件下的催化反应 -
代表性论文专著
1) Xiaoyu Wu, Wei Liu, Liqun Yang, Yue Wang, Tianwen Liu, Yao Yuan, Yan Lu*, and Zhaoguo Zhang*, Nickel-Catalyzed Regioselective Hydrosilylation of Conjugated Dienes, Chin. J. Chem. 2024,42, 13−19.
2) Yan Lu, Qi Gu, Stephen F. Martin*, Structure-affinity relationships of stereoisomers of norbenzomorphan-derived σ2R/TMEM97 modulators, Eur. J. Med. Chem. 2023, 257, 115488
3) Yuxuan Zhang, Xiaotong Li, Limin Xu, Xiaomin Xie, Yan Lu*, and Zhaoguo Zhang*, Ru-Catalyzed Enantioselective Hydrogenation of Diaryl 1,4-Diketones: Synthesis of Chiral 1,4-Diarylbutane-1,4-Diols, Org. Lett. 2022, 24, 7512−7516.
4) Yuxuan Zhang, Limin Xu, Yan Lu*, Zhaoguo Zhang*, Progress in Asymmetric Catalytic Reduction of Diketones, Chin. J. Org. Chem. 2022, 42, 3221−3239.
5) Jing Jin#, Nicolas Arbez#, James J. Sahn#, Yan Lu#, Kathryn T. Linkens, Timothy R. Hodges, Anthony Tang, Robyn Wiseman, Stephen F. Martin*, and Christopher A. Ross*, Neuroprotective Effects of σ2R/TMEM97 Receptor Modulators in the Neuronal Model of Huntington’s Disease, ACS Chem. Neurosci. 2022, 13, 2852–2862.
6) Yan Lu, Yuhang Zhou, Jingchuan Zhang, Lili Lin*, Xiaohua Liu, and Xiaoming Feng*, Highly Regio- and Enantioselective Nitroso Diels−Alder Reaction of 1,3-Diene-1-carbamates Catalyzed by Chiral N,N′-Dioxide/Copper(II) Complex, Adv. Synth. Catal. 2018, 360, 186–191.
7) Yan Lu, Yuhang Zhou, Lili Lin*, Haifeng Zheng, Kai Fu, Xiaohua Liu, and Xiaoming Feng*, N,N′-Dioxide/Nickel(II)-Catalyzed Asymmetric Diels-Alder Reaction of Cyclopentadiene with 2,3-Dioxopyrrolidines and 2-Alkenoyl Pyridines, Chem. Commun. 2016, 52, 8255–8258.
8) Yan Lu, Min Wang, Xiaohu Zhao, Xiaohua Liu*, Lili Lin, Xiaoming Feng*, Cooperative Chiral Guanidine/AgPF6 Catalyzed Asymmetric Isocyanoacetate Aldol Reaction with Isatins, Synlett 2015, 26, 1545–1548.
9) Yuhang Zhou, Lili Lin, Xiaohua Liu*, Xinyue Hu, Yan Lu, Xiying Zhang, and Xiaoming Feng*, Catalytic Asymmetric Diels-Alder Reaction/[3,3] Sigmatropic Rearrangement Cascade of 1-Thiocyanatobutadienes, Angew. Chem. Int. Ed. 2018, 57, 9113–9116.
10) Jingchuan Zhang, Kai Fu, Lili Lin*, Yan Lu, Xiaohua Liu, and Xiaoming Feng*, Efficient Catalytic Enantioselective Hydroxyamination of α-Aryl-α-Cyanoacetates with 2-Nitrosopyridines, Chem. Eur. J. 2018, 24, 4289–4293.
11) Xinyue Hu, Yuhang zhou, Yan Lu, Sijia Zou, Lili Lin*, Xiaohua Liu, and Xiaoming Feng*, Catalytic Asymmetric Inverse-Electron-Demand Hetero-Diels−Alder Reaction of Dioxopyrrolidines with Hetero-Substituted Alkenes, J. Org. Chem. 2018, 83, 8679–8687.
12) Yuhang Zhou, Yan Lu, Xinyue Hu, Hongjiang Mei, Lili Lin*, Xiaohua Liu, and Xiaoming Feng*, Highly Diastereo- and Enantioselective Synthesis of Spirooxindolecyclohexaneamides through N,N′-Dioxide/Ni(II)-Catalyzed Diels-Alder Reactions, Chem. Commun. 2017, 53, 2060–2063.
13) Tengfei Kang, Shulin Ge, Lili Lin, Yan Lu, Xiaohua Liu*, Xiaoming Feng*, A Chiral N,N′-Dioxide–ZnII Complex Catalyzes the Enantioselective [2+2] Cycloaddition of Alkynoneswith Cyclic Enol Silyl Ethers, Angew. Chem. Int. Ed. 2016, 55, 5541–5544.
14) Ruixue Peng, Lili Lin*, Yuheng Zhang, Wangbin Wu, Yan Lu, Xiaohua Liu and Xiaoming Feng*, The assignment of the configuration for α-hydroxy acid esters using a CEC strategy, Org. Biomol. Chem. 2016, 14, 5258–5262.
