周永丰教授

办公电话:021-54742664
电子邮件:yfzhou@sjtu.edu.cn
通讯地址:上海市东川路800号化学化工学院A楼525室

  • 教育背景

    1995-1999:哈尔滨工业大学理学院,学士
    1999-2001:哈尔滨工业大学理学院,硕士
    2001-2005:上海交通大学化学化工学院,博士
    2013:伊利诺伊大学厄巴纳-香槟分校,高级访问学者

  • 工作经历

    2005-2006:上海交通大学化学化工学院,讲师
    2006-2010:上海交通大学化学化工学院,副教授
    2010-至今:上海交通大学化学化工学院,教授
    2008年11月:被遴选为上海交通大学高分子化学与物理专业博士生导师
    2005年-至今:上海交通大学金属基复合材料国家重点实验室固定研究人员

  • 研究方向

    1、超分子自组装
    2、嵌段共聚物的分子设计与可控合成
    3、细胞仿生自组装

  • 科研项目

    主持国家杰出青年基金、973计划项目课题、自然科学基金、教育部新世纪优秀人才支持计划、霍英东基金、全国百篇优秀博士学位论文基金、上海市科技启明星等多项课题研究。

  • 代表性论文专著

    论文

    (1) Liu, Y.; Yu, C. Y.; Jin, H. B.; Jiang, B. B.; Zhu, X. Y.; Zhou, Y. F.*; Lu, Z. Y.*; Yan, D. Y., A Supramolecular Janus Hyperbranched Polymer and Its Photoresponsive Self-Assembly of Vesicles with Narrow Size Distribution, J. Am. Chem. Soc. 2013, 135, 4765.

    (2) Dong, R. J.; Zhu, B. S.; Zhou, Y. F.*; Yan, D.Y.; Zhu, X.Y.*, Reversible photoisomerization of azobenzene containing polymeric systems driven by visible light, Polym. Chem. 2013, 4, 912.

    (3) Wang, Y. L.; Li, B.; Zhou, Y. F.*; Lu, Z. Y.*, Yan, D.Y., Dissipative Particle Dynamics Simulation Study on the Mechanisms of Self-Assembly of Large Multimolecular Micelles from Amphiphilic Dendritic Multiarm Copolymers, Soft matter 2013, 9, 3293.

    (4) Liu,Y.; Gao, Y.; Lu, Q. H.; Zhou, Y. F.*; Yan, D. Y., Bio-inspired hierarchical self-assembly of nanotubes into multidimensional and multi-scale structures, Nanoscale 2012, 4, 224.

    (5) Tao, W.; Liu, Y.; Jiang, B. B.; Yu, S. R.; Huang, W.; Zhou, Y. F.*; Yan, D.Y.; A Linear-Hyperbranched Supramolecular Amphiphile and Its Self-Assembly into Vesicles with Great Ductility, J. Am. Chem. Soc. 2012, 134, 762.

    (6) Dong, R. J.; Zhu, B. S.; Zhou, Y. F.*; Yan, D. Y.; Zhu, X. Y.*, “Breathing” Vesicles with Jellyfish-like On-Off Switchable Fluorescence Behavior, Angew. Chem. Int. Ed. 2012, 51, 11633.

    (7) Jin, H. B.; Liu, Y.; Zheng, Y. L.; Huang, W.; Zhou, Y. F.*; Yan, D.Y., Cytomimetic Large-Scale Vesicle Aggregation and Fusion Based on Host-Guest Interaction, Langmuir 2012, 28, 2066.

    (8) Jiang, B. B.; Tao, W.; Lu, X.; Liu, Y.; Jin, H. B.; Pang, Y.; Sun, X. Y. *; Yan, D. Y.; Zhou, Y. F.*, A POSS-Based Supramolecular Amphiphile and Its Hierarchical Self-Assembly Behaviors, Macromol. Rapid Commun. 2012, 33, 767.

    (9) Jin, H. B.; Huang, w.; Zheng, Y. L.; Zhou, Y. F.*; Yan, D. Y., Construction of Macroscopic Cytomimetic Vesicle Aggregates Based on Click Chemistry: Controllable Vesicle Fusion and Phase Separation, Chem. Eur. J. 2012, 18, 8641.

    (10) Jin, H. B.; Huang, w.; Zhu, X. Y.; Zhou, Y. F.*; Yan, D. Y., Biocompatible or biodegradable hyperbranched polymers: from self-assembly to cytomimetic applications, Chem. Soc. Rev. 2012, 41, 5986.

    (11)  Liu,Y.; Jin, H. B.; Zhu, S. M.; Liu, Y. C.*; Long, M. C.*; Zhou, Y. F.*; Yan, D. Y., A facile method for fabricating TiO2@mesoporous carbon and three-layered nanocomposites, Nanotechnology 2012, 23, 325602

    (12)  Yu, S. R.; Chen, J. X.; Dong, R. J.; Su, Y.; Ji, B.*; Zhou, Y. F.*; Zhu, X. Y.*; Yan, D. Y., Enhanced Gene Transfection Efficiency of PDMAEMA by Incorporating Hydrophobic Hyperbranched Polymer Cores: Effect of Degree of Branching, Polym. Chem. 2012, 3, 3324.

    (13) Jin, H. B.; Zheng, Y. L.; Liu, Y.; Cheng, H. X.; Zhou, Y. F.*; Yan, D.Y., Reversible and Large-Scale Cytomimetic Vesicle Aggregation Based on Light-Responsive Host-Guest Interactions, Angew. Chem. Int. Ed. 2011, 50, 10352.

    (14) Liu, J.Y.; Huang, W.*; Pang, Y.; Huang, P.; Zhu, X.Y.; Zhou, Y. F.; Yan, D.Y.*, Molecular Self-Assembly of A Homopolymer: An Alternative to Fabricate Drug Delivery Platform for Cancer Therapy, Angew. Chem. Int. Ed. 2011, 50, 9162.

    (15) Zhu, X.Y.; Zhou, Y. F.*; Yan, D. Y.* Influence of Branching Architecture on Polymer Properties, J. Polym. Sci., Part B: Polym. Phys 2011, 49, 1277.

    (16) Dong, R. J.; Liu, Y.; Zhou, Y. F.*; Yan, D.Y.; Zhu, X. Y.*, Photo-Reversible Supramolecular Hyperbranched Polymer Based on Host-Guest Interactions, Polym. Chem. 2011, 2, 2771.

    (17) Cheng; H. X.; Deng; H.; Zhou; L. Z.; Su; Y.; Yu; S. R.; Zhu; X. Y.; Zhou, Y. F.*; Yan, D. Y., Improvement of gene delivery of PDMAEMA by incorporating a hyperbranched polymer core, J. Control. Release 2011, 152, E187.

    (18) Liu, J.Y.; Pang, Y.; Huang, W.*; Zhu, Z. Y.; Zhu, X. Y.; Zhou, Y. F.; Yan, D.Y.*, Redox-Responsive Polyphosphate Nanosized Assemblies: A Smart Drug Delivery Platform for Cancer Therapy, Biomacromolecules 2011, 12, 2407.

    (19) Liu, J.Y.; Pang, Y.; Huang, W.*; Huang, X.H.; Meng, L. L.; Zhu, X. Y.; Zhou, Y. F.; Yan, D.Y.*, Bioreducible Micelles Self-Assembled from Amphiphilic Hyperbranched Multiarm Copolymer for Glutathione-Mediated Intracellular Drug Delivery, Biomacromolecules 2011, 12, 1567.

    (20) Dong, W.Y.; Cheng, H.X.; Yao, Y.A.; Zhou, Y. F.; Tong, G.S.; Yan, D.Y.; Lai, Y.J.; Li, W., Bioinspired Synthesis of Calcium Carbonate Hollow Spheres with a Nacre-Type Laminated Microstructure, Langmuir 2011, 27, 366.

    (21)  Cheng, H. X.; Yuan, X.J.; Sun, X.Y.; Li, K.P.; Zhou, Y. F.*; Yan, D. Y.*, Effect of Degree of Branching on the Self-Assembly of Amphiphilic Hyperbranched Multiarm Copolymers,Macromolecules 2010, 43, 1143.

    (22) Wang, R.B.; Zhou, L. Z.; Zhou, Y. F.; Li, G. L.; Zhu, X. Y.*; Gu, H. C.; Jiang, X. L.; Li, H. Q.; Wu, J. l.; He, L.; Guo, X. Q.; Zhu, B. S.; Yan, D. Y., Synthesis and Gene Delivery of Poly(amido amine)s with Different Branched Architecture, Biomacromolecules 2010, 11, 489.

    (23) Cheng, H. X.; Xie, S. A.; Zhou, Y. F.*; Huang, W.; Yan, D. Y.; Yang, J.T.; Ji, B. Effect of Degree of Branching on the Thermoresponsive Phase Transition Behaviors of Hyperbranched Multiarm Copolymers: Comparison of Systems with LCST Transition Based on Coil-to-Globule Transition or Hydrophilic-Hydrophobic Balance, J. Phys. Chem. B 2010, 114, 6291.

    (24)  Guo, B.; Sun X.Y.; Zhou, Y. F.*; Yan, D. Y.*, Supramolecular self-assembly and controllable drug release of thermosensitive hyperbranched multiarm copolymers, Sci. China Ser. B-Chem. 2010, 53, 487.

    (25)  Zhai, S.; Hong, H. Y.; Zhou, Y. F.*; Yan, D. Y.*, Synthesis of cationic hyperbranched multiarm copolymer and its application in self-reducing and stabilizing gold nanoparticles, Sci. China Ser. B-Chem. 2010, 53, 1114.

    (26) Sun, X. Y.; Zhou, Y. F.*; Yan, D. Y., Rendering Hyperbranched Polyglycerol Adjustably Thermoresponsive by Adamantyl Modification and Host/Guest Interaction, Macromol. Chem. Phys. 2010, 211, 1940.

    (27) Sun, X. Y.; Huang, W.; Zhou, Y. F.*; Yan, D. Y., Facile Fabrication of Narrowly-Distributed Polymeric Micelles via Host-Guest Inclusion Complexation of Hyperbranched Polymers and Cyclodextrin and its Two-Dimensional Self-assembly, Phys. Chem. Chem. Phys. 2010, 12, 11948.

    (28) Zheng, Y. L.; Zhong, L.; Huang, W.; Zhou, Y. F.*; Yan, D. Y., “Flocculation-Resistant Multimolecular Micelles with Thermo-Responsive Corona from Dendritic Heteroarm Star Copolymers”, J. Polym. Sci., Part A: Polym. Chem. 2010, 48, 4428.

    (29) Jin, H. B.; Zhou, Y. F.*; Huang, W.; Yan, D. Y., “Polymerization-like Multilevel Hierarchical Self-Assembly of Polymer Vesicles into Macroscopic Superstructures with Controlled Complexity”, Langmuir 2010, 26, 14512.

    (30)  Zhou, Y. F.; Huang, W.; Liu, J. Y.; Zhu, X. Y.*; Yan, D. Y.*, Self-Assembly of Hyperbranched Polymers and Its Biomedical Applications, Adv. Mater. 2010, 22, 4567.

    (31) Liu, J. Y.; Pang, Y.; Huang, W.*; Zhai, X.; Zhu, X. Y.; Zhou, Y. F.; Yan, D. Y.*, Controlled Topological Structure of Copolyphosphates by Adjusting Pendant Groups of Cyclic Phosphate Monomers, Macromolecules 2010, 43, 8416.

    (32) Liu, J.Y.; Huang, W.*; Pang, Y.; Zhu, X.Y.; Zhou, Y. F.; Yan, D.Y.*, Self-Assembled Micelles from an Amphiphilic Hyperbranched Copolymer with Polyphosphate Arms for Drug Delivery, Langmuir 2010, 26, 10585.

    (33) Liu, J.Y.; Huang, W.*; Pang, Y.; Zhu, X. Y.; Zhou, Y. F.; Yan, D.Y.*, The in vitro biocompatibility of self-assembled hyperbranched copolyphosphate nanocarriers, Biomaterials 2010, 31, 5643.

    (34) Liu, J.Y.; Pang, Y.; Huang, W.*; Zhu, X.Y.; Zhou, Y. F.; Yan, D.Y.*, Hyperbranched Polyphosphates for Drug Delivery Application: Design, Synthesis, and In Vitro Evaluation, Biomacromolecules 2010, 11, 1564.

    (35) Liu, J.Y., Pang, Y.; Huang, W.; Zhu, X.Y., Zhou, Y. F.; Yan, D.Y., Self-Assembly of phospholipid-analogous hyperbranched polymers nanomicelles for drug delivery, Biomaterials 2010, 31, 1334.

    (36) Dong, W. Y.; Zhou, Y. F.; Yan, D. Y.*; Mai, Y. Y.; He, L.; Jin, C., Honeycomb-Structured Microporous Films Made from Hyperbranched Polymers by the Breath Figure Method, Langmuir 2009, 25, 173.

    (37) Zhou, Y. F.*; Yan, D. Y.*, Supramolecular self-assembly of amphiphilic hyperbranched polymers at all scales and dimensions: progress, characteristics and perspectives, Chem. Commun. 2009, 1172.

    (38) Gao, Y.; Zhou, Y. F.*; Yan, D. Y.*, Preparation of polystyrene-grafted titanate nanotubes by in situ atom transfer radical polymerization, Sci. China Ser. B-Chem. 2009, 52, 344.

    (39) Cheng, H. X.; Wang, S. G.; Yang, J. T.; Zhou, Y. F.*; Yan, D. Y. *, Synthesis and self-assembly of amphiphilic hyperbranched polyglycerols modified with palmitoyl chloride, J. Colloid Interface Sci. 2009, 337, 278.

    (40)  Guo, B.; Shi, Z. Q.; Yao, Y.; Zhou, Y. F.*; Yan, D. Y.*, Facile Preparation of Novel Peptosomes through Complex Self-Assembly of Hyperbranched Polyester and Polypeptide, Langmuir 2009, 25, 6622.

    (41) Gao, Y.; Zhou, Y. F.*; Yan, D. Y.*, Temperature-sensitive and highly water-soluble titanate nanotubes, Polymer 2009, 50, 2572.

    (42) Zhang, Y. W.; Huang, W.*; Zhou, Y. F.; Yan, D. Y.*, Complex Self-Assembly of Hyperbranched Polyamidoamine/Linear Polyacrylic Acid in Water and Their Functionalization, J. Phys. Chem. B 2009, 113, 7729.

    (43) Sun, X. Y.; Zhou, Y. F.*; Yan, D. Y.*, Drug release property of a pH-responsive double-hydrophilic hyperbranched graft copolymer, Sci. China Ser. B-Chem. 2009, 52, 1703.

    (44) Hong, H. Y.; Mai, Y. Y.; Zhou, Y. F.*; Yan, D. Y.*; Chen, Y., Synthesis and Supramolecular Self-Assembly of Thermosensitive Amphiphilic Star Copolymers Based on a Hyperbranched Polyether Core, J. Polym. Sci., Part A: Polym. Chem. 2008, 46, 668.

    (45) Shi, Z. Q.; Zhou, Y. F.*; Yan, D. Y., Facile Fabrication of pH-Responsive and Size-Controllable Polymer Vesicles From a Commercially Available Hyperbranched Polyester”, Macromol. Rapid Commun. 2008, 29, 412.

    (46) Zhong, L.; Zhou, Y. F.*; Yan, D. Y.*, Pan, C. Y., Synthesis of a Multi Alternating-Arm-Containing Dendritic Star Copolymer by RAFT and Cationic Ring-Opening Polymerization, Macromol. Rapid Commun. 2008, 29, 1385.

    (47) Guo, Z.; Zhang, Y. W.; Huang, W.*; Zhou, Y. F.; Yan, D. Y., Terminal modification with 1-adamantylamine to endow hyperbranched polyamidoamine with thermo-/pH-responsive properties, Macromol. Rapid Commun. 2008, 29, 1746.

    (48) Gao, Y.; Gao, X.; Zhou, Y. F.*; Yan, D. Y.*, Preparation of poly(methyl methacrylate) grafted titanate nanotubes by in situ atom transfer radical polymerization, Nanotechnology 2008, 19, 495604.

    (49) Zhou, Y. F.; Yan, D. Y.*; Dong, W. Y.; Tian, Y., Temperature-Responsive Phase Transition of Polymer Vesicles: Real-Time Morphology Observation and Molecular Mechanism, J. Phys. Chem. B 2007, 111, 1262.

    (50) Dong, W. Y.; Zhou, Y. F.*; Yan, D. Y.*; Li, H.; Liu, Y., pH-responsive self-assembly of carboxyl-terminated hyperbranched polymers, Phys. Chem. Chem. Phys. 2007, 9, 1255.

    (51) Hong, H. Y.; Mai, Y. Y.; Zhou, Y. F.*; Yan, D. Y.*; Cui, J., Self-Assembly of Large Multimolecular Micelles from Hyperbranched Star Copolymers, Macromol. Rapid Commun. 2007, 28, 591.

    (52) Zhang, Y. W.; Huang, W.*; Zhou, Y. F.; Yan, D. Y.*, A physical gel made from hyperbranched polymer gelator, Chem. Commun. 2007, 2587–2589.

    (53) Mai, Y. Y.; Zhou, Y. F.*; Yan, D. Y.*, Real-Time Hierarchical Self-Assembly of Large Compound Vesicles from an Amphiphilic Hyperbranched Multiarm Copolymer, Small 2007, 3, 1170 – 1173.

    (54) Shi, Z. Q.; Gao, X.; Song, D.; Zhou, Y. F.*; Yan, D. Y.*, Preparation of poly(ɛ-caprolactone) grafted titanate nanotubes, Polymer 2007, 48, 7516

    (55) Shi, Z. Q.; Zhou, Y. F.; Yan, D. Y.*, Preparation of robust poly(ε-caprolactone) hollow spheres with controlled biodegradability, Macromol. Rapid Commun. 2006, 27, 1265. (AUG)

    (56) Shi, Z. Q.; Zhou, Y. F.; Yan, D. Y.*, Preparation of poly(beta-hydroxybutyrate) and poly(lactide) hollow spheres with controlled wall thickness, Polymer 2006, 47, 8073.

    (57) Mai, Y. Y.; Zhou, Y. F.*; Yan, D. Y.*; Hou, J., Quantitative Dependence of Crystallinity on Degree of Branching for Hyperbranched Poly[3-ethyl-3-(hydroxymethyl)oxetane], New J. Phys. 2005, 7 (42).

    (58) Zhou, Y. F.; Yan, D. Y.*, Real-Time Membrane Fission of Giant Polymer Vesicles, Angew. Chem. Int. Ed. 2005, 44, 3223.

    (59) Huang, W.; Zhou, Y. F.; Yan, D. Y.*, Direct Synthesis of Amphiphilic Block Copolymers from Glycidyl Methacrylate and Poly(ethylene glycol) by Cationic Ring-Opening Polymerization and Supramolecular Self-Assembly Thereof, J. Polym. Sci., Part A: Polym. Chem. 2005, 43, 2038.

    (60) Zhou, Y. F.; Yan, D. Y.*, Real-Time Membrane Fusion of Giant Polymer Vesicles, J. Am. Chem. Soc. 2005, 127, 10468.

    (61) Mai, Y. Y.; Zhou, Y. F.*; Yan, D. Y.*, Synthesis and Size-Controllable Self-Assembly of A Novel Amphiphilic Hyperbranched Multi-Arm Copolyether, Macromolecules 2005, 38, 8679.

    (62) Gong, W.; Mai, Y. Y.; Zhou, Y. F.; Qi, N.; Wang, B.*; Yan, D. Y.*, Effect of the degree of branching on atomic-scale free volume in hyperbranched poly[3-ethyl-3-(hydroxymethyl)oxetane], A positron study, Macromolecules 2005, 38, 9644

    (63) Jia, Z. F.; Zhou, Y. F.; Yan, D. Y.*, Amphiphilic star-block copolymers based on a hyperbranched core: Synthesis and supramolecular self-assembly, J. Polym. Sci., Part A: Polym. Chem. 2005, 43, 6534.

    (64) Zhou, Y. F.; Yan, D. Y.*, Supramolecular Self-Assembly of Giant Polymer Vesicles With Controlled Size, Angew. Chem. Int. Ed. 2004, 43, 4896.

    (65) Yan, D. Y.; Zhou, Y. F.; Hou, J., Supramolecular Self-assembly of Macroscopic Tubes, Science, 2004, 303, 65..


    9、邀请报告

    • Synthesis and self-assembly of hyperbranched-based supramolecular polymers. 3rd Chemical Science Symposium on Functional Supramolecular Materials. Hangzhou, June. 2013, Invited.

    • Hyperbranched-based supra-molecular polymers. SINO‐FRENCH WORSHOP Nanostructured polymers and nanohybrides:Towards properties and functions. Shanghai, June. 2013, Invited.

    • Hyperbranched-based supramolecular polymers. Australian Technology Network (ATN)/Shanghai Jiao Tong University Joint Research Workshop. Shanghai, April. 2013, Invited.

    • Hyperbranched-based supra-molecular polymers and their self-assembly behaviors. 1st China-Australia Polymer Mission. Shanghai, Janu. 2013, KeyNote.

    • Hyperbranched-based supra-molecular amphiphiles and their self-assembly behaviors. The 5th International Symposium on Polymer Chemistry. Changchun, China. June, 2012. Invited.

    • Cytomimetic chemistry based on hyperbranched polymer vesicles, 3rd Sino-French Bilateral Seminar on Macromolecules and Soft Matter. Hefei, China. Sep. 2012. Invited.

    • Stimuli-Responsive Hyperbranched Polymers and Their Self-Assemblies. The 94th Canadian Chemistry Conference and Exhibition (CSC2011), Montreal, Canada. June, 2011. Invited.

    • Self-Assembly of Hyperbranched Polymers and Its Biomedical Applications. Japan-China Joint Symposium on Functional Supramolecular Architectures. Changchun, China. July, 2010. Invited.

    • Self-Assembly of Hyperbranched Polymers and Its Biomedical Applications. The Second Sino-French Seminar at the ESPCI ParisTech, Paris, French. Oct. 2010. Invited.

    • Supramolecular Self-Assembly of Hyperbranched Polymers at All Scales and Dimensions. S-China Workshop for Early Career Chemical Scientists—SUPRAMOLECULAR CHEMISTRY. Beijing, China. Oct. 2009. Invited.

    • Supramolecular Self-Assembly of Hyperbranched Polymers at All Scales and Dimensions. The 6th International Dendrimer Symposium (IDS 6). Stockholm, Sweden. June, 2009. KeyNote.


  • 荣誉奖励

    1、2012年度  国家杰出青年基金
    2、2009年度  国家自然科学二等奖(第二完成人)
    3、2008年度  全国百篇优秀博士学位论文奖
    4、2007年度  上海市自然科学一等奖(第二完成人)
    5、2007年度  入选教育部新世纪优秀人才计划
    6、2006年度  入选上海市青年科技启明星计划
    7、2006年度  获中国化学会-约翰威立出版公司青年化学论文奖 

  • 教学工作

    1、本科生:《生物医药高分子》
    2、研究生:《学术前沿进展》

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