董朝青研究员

办公电话:021-54746001
电子邮件:cqdong@sjtu.edu.cn
通讯地址:上海市东川路800号化学化工学院A楼216室
个人主页: https://www.researchgate.net/profile/Chaoqing-Dong

  • 教育背景

    1997-2001:湖南中南大学化学化工学院,学士
    2001-2004:湖南中南大学化学化工学院,硕士
    2004-2007:上海交通大学化学化工学院,博士

  • 工作经历

    2007-2011:上海交通大学化学化工学院,讲师

    2011-2012:美国普度大学,博士后
    2012-2018:上海交通大学化学化工学院,副研究员
    2019-    :上海交通大学化学化工学院,研究员

  • 研究方向

    (1)生物分析;

    (2)单分子/单颗粒分析方法研究

    (3)单分子/单颗粒分析仪器研究

  • 科研项目

    主持了国家自然科学基金面上项目、青年基金、教育部博士点基金项目、上海市科委自然科学基金项目、上海市教委科研重点项目、上海市人事局人才发展基金项目、上海市教育发展基金项目等多项课题研究,参加了国家自然科学基金重点项目、国家重大科学仪器研制项目、科技部863计划、上海市基础研究重点项目、上海市纳米专项等项目。

  • 代表性论文专著

    论文

    Chaoqing DongJicun Ren*. Resonance Light-Scattering Correlation Spectroscopy and Its Application in Analytical Chemistry for Life Science. Accounts of Chemical Research  2023, 56, 19, 2582-2594. 

    Tian Zhang, Chaoqing Dong*, and Jicun Ren. Probing the Protein Corona of Nanoparticles in a Fluid Flow by Single-Particle Differenced Resonance Light Scattering Correlation Spectroscopy. Analytical Chemistry,2023, 95, 3, 2029–2038.

    Jie Yang, Chaoqing Dong*, Aidi Zhang, and Jicun Ren. Quantification of mRNA in Single Cells Based on Dimerization-Induced Photoluminescence Nonblinking of Quantum Dots. Analytical Chemistry, 2022, 94, 36, 12407–12415.

    Luoyu Ding, Tian Zhang, Chaoqing Dong,* and Jicun Ren*. Brightness Analysis per Moving Particle: In Situ Analysis of Alkaline
    Phosphatase in Living Cells. Analytical Chemistry, 2022, 94, 5181-5189.

    Chaoqing Dong*, Qing Wang, Zhenli Xu, Liyun Deng, Tian Zhang, Binglin Lu, Qin Wang*, and Jicun Ren*. The Theoretical Model, Method, and Applications of Scattering Photon Burst Counting Based on an Objective Scanning Technique. Analytical Chemistry, 2021, 93(37), 12556–12564.

    Tian Zhang, Haohan Song, Liyun Deng, Chaoqing Dong*, and Jicun Ren*. Single-Particle Catalytic Analysis by a Photon Burst Counting Technique Combined with a Microfluidic Chip. Analytical Chemistry, 2021, 93(28), 9752–9759

    Fucai Li, Zhixue Du, Xiangyi Huang, Chaoqing Dong*, and Jicun Ren*. Analyses of p73 Protein Oligomerization and p73-MDM2 Interaction in Single Living Cells Using in Situ Single Molecule Spectroscopy. Analytical Chemistry, 2021, 93(2), 886–894.

    Jinchun Xu, Yaoqi Liu, Fucai Li, Liyun Deng, Chaoqing Dong,* and Jicun Ren*.In Situ Assay of Proteins Incorporated with Unnatural Amino Acids in Single Living Cells by Differenced Resonance Light Scattering correlation Spectroscopy. Analytical Chemistry, 2021, 93, 9329−9336.

    Shengrong Yu, Fucai Li, Xiangyi Huang, Chaoqing Dong*, and Jicun Ren*. In Situ Study of Interactions between Endogenous c-myc mRNA with CRDBP in a Single Living Cell by Combining Fluorescence Cross-Correlation Spectroscopy with Molecular Beacons, Analytical Chemistry, 2020, 92(4), 2988–2996

    Fucai Li, Shengrong Yu, Xiangyi Huang, Chaoqing Dong*, and Jicun Ren*. Studying Homo-oligomerization and Hetero-oligomerization of MDMX and MDM2 Proteins in Single Living Cells by Using In Situ Fluorescence Correlation Spectroscopy. Biochemistry 2021, 60, 19, 1498–1505.

    Zhao-Jun Yan, Dongdong Wang, Zhongju Ye, Ting Fan, Gang Wu, Liyun Deng, Lu Yang, Binxiao Li, Jianwei Liu, Tonghui Ma, Chaoqing Dong, Zhan-Ting Li, Lehui Xiao*, Yunfeng Wang*, Wenning Wang*, and Jun-Li Hou*. Artificial Aquaporin That Restores Wound Healing of Impaired Cells. Journal of the American Chemical Society, 2020, 142(37), 15638–15643.

    Jie Jiang, Xueli Chen, Liya Sun, Ying Qing, Xuhan Yang, Xiaowen Hu, Chao Yang, Tianle Xu, Jijun Wang, Peng Wang, Lin He, Chaoqing Dong*, and Chunling Wan*. Analysis of the concentrations and size distributions of cell-free DNA in schizophrenia using fluorescence correlation spectroscopy. Translational Psychiatry, 2018, 8(1), 153

    Zhixue Du, Jing Yu, Fucai Li, Liyun Deng, Fang Wu, Xiangyi Huang, Jan Bergstrand, Jerker Widengren, Chaoqing Dong* and Jicun Ren* In situ monitoring p53 protein and MDM2 protein interaction in single living cells using single molecule fluorescence spectroscopy, Anal. Chem., 2018, 90, 6144−6151.

     Di Su, Xiangyi Huang,Chaoqing Dong* and Jicun Ren* .Quantitative Determination of Telomerase Activity by Combining Fluorescence Correlation Spectroscopy with Telomerase Repeat Amplification Protocol, Anal. Chem., 2018, 90, 10006-1013. 

    Bocheng Zhang, Heng Liu, Xiangyi Huang, Chaoqing Dong* and Jicun Ren* Size Distribution of Noble Metal Nanoparticles Characterized by Combing Resonance Light Scattering Correlation Spectroscopy with Maximum Entropy Method , Anal. Chem., 2017, 89 (22), 12609–12616.

    Di Su, Xiaocai Hu, Chaoqing Dong*, and Jicun Ren* Determination of caspase-3 activity and its inhibition constant by combination of fluorescence correlation spectroscopy with a microwell chip, Anal. Chem., 2017, 89, 9788−9796.

    Jinjie Wang, Xiangyi Huang, Heng Liu,Chaoqing Dong*, Jicun Ren* .Fluorescence and scattering light cross correlation spectroscopy and its applications in homogeneous immunoassay, Anal. Chem., 2017,89, 5230−5237.  

    Aidi Zhang, Chaoqing Dong*, and Jicun Ren* Tuning Blinking Behavior of Highly Luminescent Cesium Lead Halide Nanocrystals through Fast Anion-Exchange Reactions, J. Phys. Chem. C, 2017, 121, 13314−13323.

    Dong C.Q.*, Liu H., Zhang A. D., Ren J. C.*,Controllable Blinking-to-Nonblinking Behavior of Aqueous CdTeS Alloyed Quantum Dots, Chem. Eur. J. 2014, 20:1940-1946.
    Dong C.Q.*, Liu H., Ren J. C.*, Assessing the Blinking State of Fluorescent Quantum Dots in Free Solution by Combining Fluorescence Correlation Spectroscopy with Ensemble Spectroscopic Methods. Langmuir 2014, 30, 12969−12976

    Dong C.Q., Ren J. C.*, Coupling of fluorescence correlation spectroscopy with capillary and microchannel analytical systems and its applications. Electrophoresis. 2014, 35:2267-2278.
    Zhang B. C., Lan T., Huang X. Y., Dong C.Q.*, Ren J. C.*, Optical Trapping Effect and Its Calibration Method in Resonance Light Scattering Correlation Spectroscopy of Gold Nanoparticles in Solution, J. Phys. Chem. C, 2014, 118: 14495−14501.
    Liu H., Dong C.Q., Ren J. C.*, Tempo-spatially resolved scattering correlation spectroscopy under dark-field illumination and its application to investigate dynamic behaviors of gold nanoparticles in live cells. J Am Chem Soc. 2014,136:2775-2285.
    Dong C.Q., Irudayaraj, J.*, Hydrodynamic size-dependent cellular uptake of aqueous QDs probed by fluorescence correlation spectroscopy. J. Phys. Chem. B 2012,116: 12125-12132.
    Dong C.Q., Ren J. C.*, On-line investigation of laser-induced aggregation and photo-activation of CdTe quantum dots by fluorescence correlation spectroscopy, J. Phys. Chem. C, 2007, 111: 7918-7923.
    Dong C.Q., Qian H. F., Fang N,H., Ren J. C.*, Study of Fluorescence Quenching and Dialysis Process of CdTe Quantum Dot Using Ensemble Techniques and Fluorescence Correlation Spectroscopy, J. Phys. Chem. B, 2006, 110:11069-11075.
    Dong C.Q., Rui Bi, Qian H. F., Ren J. C.*. Coupling fluorescence correlation Spectroscopy with Microchip Electrophoresis to Determine Effective Surface Charge of Water-Soluble QDs, Small, 2006, 2:534-538.


  • 软件版权登记及专利

    发明专利:

    1)发明人:董朝青、任吉存发明名称:用于三种分子间结合作用解析的荧光三元相关光谱系统. 专利号:ZL 202110563055.3

    2)美国发明专利:Chaoqing Dong, Jicun Ren. Fluorescence triple-correlation spectroscopy system for analyzing interaction between three kinds of molecules. Patent No. US 11530988B1.

    3)发明人:任吉存、董朝青.  发明名称:水溶性长链巯基类化合物包覆的碲化镉量子点合成方法. 专利号:ZL 200810034005.0


  • 荣誉奖励

    1、上海市晨光学者(2008年)

    2.   上海市人才发展基金(2020年)

  • 教学工作

    1、本科生:《分析化学2》(原《仪器分析》)

    2、本科生:《大学化学实验》

    3、研究生:《现代光学分析方法》

  • 人才需求

    目前尚有2024年秋季待入学的硕士生名额。

    欢迎博士后、博士生、硕士生、本科生加入我们科研团队。

地址:上海市东川路800号 200240
电话:021-54742893
E-mail:sjtuscce@sjtu.edu.cn

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