2005-2009 福州大学，理学学士
2009-2014 兰州大学，理学博士，专业：有机化学，导师：涂永强院士

2014.7-2017.11  上海交通大学，专职科研博士后，合作导师：涂永强院士

2015.7-2017.8   美国犹他大学，博士后，导师：Prof. Matthew S. Sigman
2017.12 -至今   上海交通大学化学化工学院，长聘教轨副教授，博士生导师

1. 发展含硫、硒、碲化合物的不对称合成新策略；

2. 设计、合成新型的手性硫、硒、碲催化剂并研究其催化性能和机制；

3. 设计、合成新型的硫、硒、碲试剂并研究其反应活性；

4. 开展有机硫、硒化合物的不对称合成策略在天然产物和药物分子合成中的应用；

5. 开展手性含硫、硒、碲化合物的生物活性和功能应用研究。

主持国家自然科学面上项目（2项）、青年基金（1项，已结题）、上海市教委（1项）、上海交通大学启动经费，功能有机分子化学国家重点实验室开放课题（2021-2023）。

29. Deng Zhu+, Lu Yu+, Hui-Yun Luo, Xiao-Song Xue*, Zhi-Min Chen*

Atroposelective Electrophilic Sulfenylation of N-Aryl Aminoquinone Derivatives Catalyzed by Chiral SPINOL-Derived Sulfide

Angew. Chem. Int. Ed. 2022, 61, e202211782 (Hot Paper, 10.1002/anie.202211782). 

28. Hui-Yun Luo, Zi-Hao Li, Deng Zhu, Qin Yang, Ren-Fei Cao, Tong-Mei Ding, Zhi-Min Chen*

Chiral Selenide/Achiral Sulfonic Acid Co-catalyzed Atroposelective Sulfenylation of Biaryl Phenols via a Desymmetrization/Kinetic Resolution Sequence

J. Am. Chem. Soc. 2022, 144, 2943-2952.

27. Xiao-Dong Liu⁺, Yicong Luo⁺, Xiaohong, Huo, Hui-Yun Luo, Ren-Fei Cao, Zhi-Min Chen*

Chiral Sulfide/Phosphoric Acid Cocatalyzed Enantioselective Intermolecular Oxysulfenylation of Alkenes with Phenol and Alcohol O-nucleophiles

CCS Chem., 2022, 4, 3342-3354.

26. Yu-Yang Xie, Zhi-Min Chen,* Hui-Yun Luo, Hui Shao, Yong-Qiang Tu,* Xiaoguang Bao,* Ren-Fei Cao, Shu-Yu Zhang, Jin-Miao Tian

Lewis Base/Brønsted Acid Cocatalyzed Enantioselective Sulfenylation/Semipinacol Rearrangement of Di- and Trisubstituted Allylic Alcohols

Angew. Chem. Int. Ed. 2019, 58, 12491-12496. Featured by Benjamin List, Joyce A. A. Grimm in SYNFACTS 2019, 15, 1175.

25. Xiao-Dong Liu, Ai-Hui Ye, Zhi-Min Chen*

Catalytic Enantioselective Intermolecular Three-Component Sulfenylative Difunctionalizations of 1,3-Dienes

ACS Catal. 2023, 13, 2715-2722.

24. Deng Zhu, Zhi-Min Chen*

Application of Chiral Lewis Base/Brønsted Acid Synergistic Catalysis Strategy in Enantioselective Synthesis of Organic Sulfides 

Chin. J. Org. Chem. 2022, 42, 3015-3032. (invited submission)

23. Hui-Yun Luo, Yu-Yang Xie, Xu-Feng Song, Jia-Wei Dong, Deng Zhu, Zhi-Min Chen*

Lewis base-catalyzed asymmetric sulfenylation of alkenes: construction of sulfenylated lactones and application to the formal syntheses of (-)-nicotlactone B and (-)-galbacin

Chem. Commun., 2019, 55, 9367-9370.

22. Hui-Yun Luo, Jia-Wei Dong, Yu-Yang Xie, Xu-Feng Song, Deng Zhu, Tongmei Ding, Yuanyuan Liu,* Zhi-Min Chen*

Lewis Base/Brønsted Acid Co-catalyzed Asymmetric Thiolation of Alkenes with Acid-Controlled Divergent Regioselectivity

Chem. Eur. J. 2019, 25, 15411-15418.

21. Ren-Fei Cao⁺, Lu Yu⁺, Yu-Xuan Huo, Yao Li, Xiao-Song Xue, Zhi-Min Chen*

Chiral Lewis Base Catalyzed Enantioselective Selenocyclization of 1,1-Disubstituted Alkenes: Asymmetric Synthesis of Selenium-Containing 4H-3,1-Benzoxazines

Org. Lett. 2022, 24, 4093-4098.

20. Deng Zhu, Ai-Hui Ye, Zhi-Min Chen*

N-Selenocyanato-dibenzenesulfonimide: a new electrophilic selenocyanation reagent (Feature Article, invited submission)

Synthesis 2021, 53, 3744-3750.

19. Ai-Hui Ye, Ye Zhang, Yu-Yang Xie, Hui-Yun Luo, Jia-Wei Dong, Xiao-Dong Liu, Xu-Feng Song, Tongmei Ding, Zhi-Min Chen*

TMSCl-Catalyzed Electrophilic Thiocyano Oxyfunctionalization of Alkenes Using N-Thiocyano-dibenzenesulfonimide

Org. Lett., 2019, 21, 5106-5110.

18. Xu-Feng Song,† Ai-Hui Ye,† Yu-Yang Xie, Jia-Wei Dong, Chao Chen, Ye Zhang,* Zhi-Min Chen* (†equal contribution)

Lewis Acid Mediated Thiocyano Semipinacol Rearrangement of Allylic Alcohols for the Construction of α-Quaternary Center β-Thiocyano Carbonyls

Org. Lett., 2019, 21, 9550-9554.

17. Ai‐Hui Ye, Xu-Feng Song, Zhi‐Min Chen*

Electrophilic Thiocyanation of Tryptamine Derivatives: Divergent Synthesis of SCN-Containing Indole Compounds

Chem. Asian J. 2022, 17, e202200802 (10.1002/asia.202200802).

16. Ai‐Hui Ye, Zi-Hao Li, Tong-Mei Ding, Hua Ke*, Zhi‐Min Chen*

Phosphoric Acid Catalyzed Electrophilic Thiocyanation of Indoles: Access to SCN-Containing Aryl-Indole Compounds

Chem. Asian J. 2022, 17,  e202200256, (DOI: 10.1002/asia.202200256).

15. Kai Ji, Ka Lu, Jie Huang, Zi-Hao Li, Tong-Mei Ding, Zhi-Min Chen*

Brønsted Acid-Catalyzed Solvent-Controlled Regioselective Hydrothiolation and Diastereoselective Cascade Cyclization of Dienes

Chem. Commun., 2021, 57, 12639-12642.

14. Kai Ji, Ka Lu, Jie Huang, Zi-Hao Li, Hua Ke*, Zhi-Min Chen*

Brønsted Acid-Catalyzed Regioselective Hydrothiolation of Dienes: Solvent-Controlled Divergent Synthesis of Sulfides

Org. Lett. 2021, 23, 8028-8032.

13. Deng Zhu, Hui-Yun Luo, Zhi-Min Chen*

Selenium-Catalyzed Trifluoromethylsulfinylation/Rearrangement of Allylic and Propargylic Alcohols: Access to Allylic and Allenic Triflones

Org. Lett. 2021, 23, 1044-1048.

12. Deng Zhu, Tong-Mei Ding, Hui-Yun Luo, Hua Ke, Zhi-Min Chen*

Divergent Synthesis of Trifluoromethyl Sulfoxides and β-SCF3 Carbonyl Compounds by Tandem Trifluoromethylthiolation/Rearrangement of Allylic and Propargylic Alcohols

Org. Lett. 2020, 22, 7699-7703.

11. Xu-Feng Song, Tong-Mei Ding, Deng Zhu, Jie Huang, Zhi-Min Chen*

Lewis-Acid-Mediated Intramolecular Trifluoromethylthiolation of Alkenes with Phenols: Access to SCF3‑Containing Chromane and Dihydrobenzofuran Compounds

Org. Lett. 2020, 22, 7052-7056.

10. Chao-Chao Xi, Zhi-Min Chen*, Shu-Yu Zhang, Yong-Qiang Tu*.

Electrophilic Trifluoromethylthiolation/Semipinacol Rearrangement: Preparation of β-SCF3 Carbonyl Compounds with α-Quaternary Carbon Center.

Org. Lett., 2018, 20, 4227–4230.

9. Kai Ji†, Jie Huang†, Xin-Yu Zhang, Zhi-Min Chen*

Enantioselective 1,1-Diarylation of Allyl Sulfones Catalyzed by Palladium with a Chiral Phosphoric Acid

Chem Synth 2022;2:17. http://dx.doi.org/10.20517/cs.2022.27.

8. Jie Huang,  Zhi-Min Chen*

The alkynylative difunctionalization of alkenes

Chem. Eur. J. 2022, 28, e202201519.

7. Jie Huang, Ling-Ling Chen,  Tong-Mei Ding*, Zhi-Min Chen*

Iron-Catalyzed Hydroarylation of 1,3-Dienes with Indoles

Org. Chem. Front., 2023, 10, 461-466.

6. Jie Huang, Ling-Ling Chen,  Zhi-Min Chen*

Palladium-Catalyzed Three-Component Cross-Coupling of Conjugated Dienes with Indoles Using Ethynylbenziodazolones as Electrophilic Alkynylating Reagents

Org. Lett. 2022, 24, 5777-5781.

5. Chao Chen, Jun-Chen Kang, Chen Mao, Jia-Wei Dong, Yu-Yang Xie, Tong-Mei Ding, Yong-Qiang Tu, Zhi-Min Chen*, Shu-Yu Zhang*

Electrochemical Halogenation/Semi-pinacol Rearrangement of Allylic Alcohols Using Inorganic Halide Salt: An Eco-friendly Route to Synthesis of β-halocarbonyls

Green Chem., 2019, 21, 4014-4019. (Inside front cover)

4. Jun-Chen Kang, Yong-Qiang Tu, Jia-Wei Dong, Chao Chen, Jia Zhou, Tong-Mei Ding, Jian-Tao Zai, Zhi-Min Chen*, Shu-Yu Zhang*.

Electrochemical semipinacol rearrangements of allylic alcohols: construction of all-carbon quaternary stereocenters.

Org. Lett., 2019, 21, 2536–2540. (Most downloaded)

3. Yu-Yang Xie, Yun-Peng Wang, Xiao-Jing Zhao, Ai-Fang Wang,  Zhi-Min Chen*, Yong-Qiang Tu*.

Oxyallyl Cation Promoted Dearomative Semipinacol Rearrangement: Facile Stereodivergent Synthesis of Spiro-indolines with Contiguous Quaternary Centers

Chem. Commun., 2021, 57, 6632-6635.

2. Chao-Chao Xi, Xiao-Jing Zhao, Jin-Miao Tian*, Zhi-Min Chen*, Kun Zhang, Fu-Min Zhang, Yong-Qiang Tu*, and Jia-Wei Dong

Atroposelective Synthesis of Axially Chiral 3-Arylindoles by Copper-Catalyzed Asymmetric Cross-Coupling of Indoles with Quinones and Naphthoquinones

Org. Lett. 2020, 22, 4995-5000.

1. Jia‐Wei Dong, Tongmei Ding, Shu‐Yu Zhang*, Zhi‐Min Chen*, Yong‐Qiang Tu*.

A Facile Approach to Oximes and Ethers by a Tandem NO+‐Initiated Semipinacol Rearrangement and H‐Elimination.

Angew. Chem. Int. Ed. 2018, 57, 13192-13196.

Prior to SJTU:

8. Zhi-Min Chen†, Jianbo Liu†, Jing-Yao Guo, Maximilian Loch, Ryan Deluca, Matthew S. Sigman* (†equal contribution)

Palladium-catalyzed enantioselective alkenylation of alkenylbenzene derivatives

Chem. Sci., 2019, 10, 7246-7250.

7. Zhi-Min Chen, Christine S. Nervig, Ryan J. DeLuca, and Matthew S. Sigman*. Palladium-catalyzed enantioselective redox-relay Heck alkynylation of alkenols to access propargylic stereocenters

Angew. Chem. Int. Ed. 2017, 56, 6651-6654.

6. Zhi-Min Chen, Margaret J. Hilton, and Matthew S. Sigman*.

Palladium-catalyzed enantioselective redox-relay Heck arylation of 1,1-disubstituted homoallylic alcohols 

J. Am. Chem. Soc. 2016, 138, 11461-11464.

5. Zhi-Min Chen,† Xiao-Ming Zhang†, and Yong-Qiang Tu* (†equal contribution). Radical aryl migration reactions and synthetic applications

Chem. Soc. Rev. 2015, 44, 5220-5245.

4. Zhi-Min Chen, Zhen Zhang, Yong-Qiang Tu,* Ming-Hui Xu, Fu-Min Zhang, Chen-Chen Li, and Shao-Hua Wang*.

A Mn(III)/TEMPO-co-mediated tandem azidation/1,2-carbon migration reaction of allylic silyl ethers 

Chem. Commun. 2014, 50, 10805-10808.

3. Zhi-Min Chen, Wei Bai, Shao-Hua Wang, Bin-Miao Yang, Yong-Qiang Tu,* and Fu-Min Zhang.

Copper-catalyzed tandem trifluoromethylation/semipinacol rearrangement of allylic alcohols

Angew. Chem. Int. Ed. 2013, 52, 9781-9785.

2. Zhi-Min Chen, Bin-Miao Yang, Zhi-Hua Chen, Qing-Wei Zhang, Min Wang, and Yong-Qiang Tu*.

Organocatalytic asymmetric fluorination/semipinacol rearrangement: An efficient approach to chiral β-fluoroketones 

Chem. Eur. J. 2012, 18, 12950-12954.

1. Zhi-Min Chen, Qing-Wei Zhang, Zhi-Hua Chen, Hui Li, Yong-Qiang Tu,* Fu-Min Zhang, and Jin-Miao Tian.

Organocatalytic asymmetric halogenation/semipinacol rearrangement: highly efficient synthesis of chiral α-oxa-quaternary β-haloketones

J. Am. Chem. Soc. 2011, 133, 8818-8821.

2名研究生（罗会云，宋旭峰）获得研究生国家奖学金，4名研究生（罗会云，朱登，黄杰，陈玲玲）获得各类研究生专项奖学金，2名硕士毕业生（宋旭峰，汲凯）获得上海交通大学优秀毕业生。

授权中国发明专利4项。

2019 上海市高等学校特聘教授计划（“东方学者”）

2020 上海交通大学“教书育人奖（集体）”一等奖

本科生：《大学化学》《有机化学实验》

研究生：《现代有机合成》

欢迎热爱有机合成化学的青年学子加入课题组，共同学习、成长！