霍小红长聘(教轨)副教授

办公电话:18801966361
电子邮件:huoxiaohong@sjtu.edu.cn
通讯地址:上海市东川路800号上海交通大学化学化工学院B楼529室
个人主页: http://wanbin.sjtu.edu.cn/

  • 教育背景

    2006-2010 河南大学,应用化学,学士

    2010-2012 上海交通大学,有机化学,硕士(导师:张万斌教授)
    2013-2013  Tohoku University,有机化学,Campus Asia Program(联合导师:Prof. Ilya D. Gridnev and Prof. Masahiro Terada)
    2012-2017 上海交通大学,药学,博士(导师:张万斌教授  刘燕刚教授)

  • 工作经历

    2017-2019 上海交通大学,博士后(合作导师:张万斌教授)
    2019-至今 上海交通大学化学化工学院,特别研究员

  • 研究方向

    1)高效不对称催化
    2)重要手性药物开发和工业化研究

    3) 机理研究包括实验与理论研究

  • 科研项目

    主持国家自然科学基金青年项目、上海市“科技创新行动计划”青年科技英才扬帆计划、2018年中国博士后科学基金面上项目一等资助,并参与国家自然科学基金重点、重点国际合作和面上项目、上海市科委和教委重大和重点科技攻关项目等多项课题研究。

  • 代表性论文专著

    Jiacheng Zhang,§ Xiaohong Huo,§ Junzhe Xiao,§ Ling Zhao, Shengming Ma*, and Wanbin Zhang*,“Enantio- and Diastereodivergent Construction of 1,3-Nonadjacent Stereocenters Bearing Axial and Central Chirality through Synergistic Pd/Cu Catalysis”, J. Am. Chem. Soc. 2021, 143, 12622-12632. DOI: 10.1021/jacs.1c05087. (§co-first author)


    Youbin Peng,§ Xiaohong Huo,§ Yicong Luo, Liang Wu, and Wanbin Zhang*,“Enantio- and Diastereodivergent Synthesis of Spirocycles through Dual-Metal-Catalyzed [3+2] Annulation of 2-Vinyloxiranes with Nucleophilic Dipoles”, Angew. Chem. Int. Ed. 2021, 60, 24941-24949. DOI: 10.1002/anie.202111842. (§co-first author) Hot Paper


    Xiaohong Huo, Ling Zhao, Yicong Luo, Yue Wu, Yuwen Sun, Guanlin Li, Tatiana Gridneva, Jiacheng Zhang, Yong Ye and Wanbin Zhang*, “Stereodivergent Pd/Cu Catalysis for Asymmetric Desymmetric Alkylation of Allylic Geminal Dicarboxylates”,  CCS Chem. 2021, 3, 1933-1944. DOI: 10.31635/ccschem.021.202101044.


    Mo Wang,§ Lu Zhang,§ Xiaohong Huo,§ Zhenfeng Zhang,§ Qianjia Yuan, Panpan Li, Jianzhong Chen, Yashi Zou, Zhengxing Wu, and Wanbin Zhang*, "Catalytic Asymmetric Synthesis of the Anti-COVID-19 Drug Remdesivir”, Angew. Chem. Int. Ed. 202059, 20814-20819. DOI: 10.1002/anie.202011527. VIP


    Rui He,§ Xiaohong Huo,§ Ling Zhao, Feijun Wang, Liyin Jiang, Jian Liao,* and Wanbin Zhang*, "Stereodivergent Pd/Cu Catalysis for the Dynamic Kinetic Asymmetric Transformation of Racemic Unsymmetrical 1,3-Disubstituted Allyl Acetates", J. Am. Chem. Soc. 2020142, 8097-8103. (§co-first author)


    Guanlin Li,§ Xiaohong Huo,§ Xieyang Jiang, and Wanbin Zhang*, "Asymmetric Synthesis of Allylic Compounds via Hydrofunctionalisation and Difunctionalisation of Dienes, Allenes, and Alkynes", Chem. Soc. Rev. 202049, 2060-2118. Inside front cover (§co-first author)  (ESI Highly Cited Paper)


    Xiaohong Huo, Rui He, and Wanbin Zhang*, "Iridium/Zinc and Iridium/Copper Dual Catalysis" in SOS Reference Library: Dual Catalysis in Organic Synthesis; Gary A. Molander Ed.; 2019, accepted. Georg Thieme Verlag KG, A Thieme Group company, RuedigerstraBe 14, 70469 Stuttgart, Germany.


    Xiaohong Huo, Jiacheng Zhang, Jingke Fu, Rui He, and Wanbin Zhang*, Ir/Cu Dual Catalysis: "Enantio- and Diastereodivergent Access to α,α-Disubstituted α-Amino Acids Bearing Vicinal Stereocenters", J. Am. Chem. Soc. 2018140, 2080-2084. (ESI Highly Cited Paper)


    Xiaohong Huo, Rui He, Jingke Fu, Jiacheng Zhang, Guoqiang Yang, and Wanbin Zhang*, "Stereoselective and Site-Specific Allylic Alkylation of Amino Acids and Small Peptides via a Pd/Cu Dual Catalysis", J. Am. Chem. Soc. 2017139, 9819-9822.


    Xiaohong Huo,§ Rui He,§ Xiao Zhang, and Wanbin Zhang*, "An Ir/Zn Dual Catalysis for Enantio- and Diastereodivergent α-Allylation of α-Hydroxyketones", J. Am. Chem. Soc. 2016138, 11093-11096. (§co-first author)


    Xiaohong Huo, Guoqiang Yang, Delong Liu, Yangang Liu, Ilya D. Gridnev*, and Wanbin Zhang*, "Palladium-Catalyzed Allylic Alkylation of Simple Ketones with Allylic Alcohols and Its Mechanistic Study", Angew. Chem. Int. Ed. 201453, 6776-6780.

  • 荣誉奖励

    1)2019年上海市“科技创新行动计划”青年科技英才扬帆计划
    2)2018年上海交通大学优秀博士学位论文奖(共13名,作为毕业生代表发言)
    3)2018年上海交通大学博士后考核优秀
    4)2016年上海交通大学第一届学术之星(共10名)
    5)2016年美国化学会上海分会研究生学术成就奖二等奖
    6)2016年上海交通大学药学院“科技创新先进个人”
    7)2014年博士生国家奖学金
    8)2014年上海交通大学三好学生

地址:上海市东川路800号 200240
电话:021-54742893
E-mail:sjtuscce@sjtu.edu.cn

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