李长坤长聘副教授

办公电话:021-54738144
电子邮件:chkli@sjtu.edu.cn
通讯地址:上海市东川路800号化学化工学院B楼237 https://www.x-mol.com/groups/Li-Changkun?lang=zh

  • 教育背景

    2000.09-2004.06:北京大学化学与分子工程学院,学士
    2004.09-2010.07:北京大学化学与分子工程学院,博士,导师:王剑波教授、张艳教授

  • 工作经历

    2010.07-2012.09:日本京都大学工学院,博士后,导师:Masahiro Murakami 教授
    2012.10-2016.02:德国弗莱堡大学化学系,博士后,导师:Bernhard Breit 教授
    2016.03-至今:上海交通大学化学化工学院,特别研究员

  • 研究方向

    (1) 金属有机化学
    (2) 不对称催化
    (3) 有机合成

  • 代表性论文专著

    (17) Rh-Catalyzed Regio- and Enantioselective Allylic Phosphinylation

    Bing Li, Min Liu, Sajid Ur Rehman, and Changkun Li*

    J. Am. Chem. Soc. 2022144,  2893-2898.

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    (16)  Eantioselective Synthesis of Pyridiens with All-Carbon Quaternary Carbon Centers via Cobalt-Catalyzed Desymmetric

    [2+2+2] Cycloaddition

    Ke Li, Linsheng Wei, Minghe Sun, Bing Li, Min Liu, Changkun Li* 

    Angew. Chem. Int. Ed. 202160, 20204-20209.

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    (15)  Rhodium-Catalyzed Regio- and Enantioselective Allylic Amination of racemic 1,2-Disubstituted Allylic Phosphates.

    Wen-Bin Xu,† Minghe Sun,† Mouhai Shu, Changkun Li* (†, equal contribution)

    J. Am. Chem. Soc. 2021143, 8255-8260.

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    (14)  Rh-Catalyzed Chemodivergent Regio- and Enantioselective Allylic Alkylation of Indoles
    Minghe Sun, Min Liu, Changkun Li*

    Chem. Eur. J. 2021, 27, 3457-3462.


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    (13) Enantioselective Synthesis of 3-Allylindolizines via Sequential Rh-Catalyzed Asymmetric Allylation and Tschitschibabin Reaction
    Ke Li, Changkun Li*

    Org. Lett. 202022, 9456-9461.

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    (12) Regio- and Enantioselective Allylic Alkylation of Terminal Alkynes by Synergistic Rh/Cu Catalysis

    Wen-Yu Huang, Chun-Hua Lu, Samir Ghorai, Bing Li, Changkun Li*

    J. Am. Chem. Soc. 2020142, 15276-15281. 


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    (11) Desymmetrization construction of chiral lactones by synergistic Cu(II) complex and organic base

    Murad Ali, Changkun Li*

    Tetrahedron Lett. 2020, https://doi.org/10.1016/j.tetlet.2020.152106

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    (10) Cobalt/Bisoxazolinephosphine-Catalyzed Asymmetric Alkynylation of Isatins

    Jia-Feng Chen, Changkun Li*

    Org. Lett. 202022, 4686–4691


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    (9) Rh(I)-Catalyzed Regio- and Enantioselective Allylic Alkylation of Meldrum's Acid 

    Min Liu, Haiying Zhao,* Changkun Li.*

    Chin. Chem. Lett. 202132, 385-388.


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    (8) Cobalt-Catalyzed Regio- and Enantioselective Allylic Alkylation of Malononitriles

    Samir Ghorai, Sajid Ur Rehman, Wen-Bin Xu, Wen-Yu Huang, Changkun Li.*

    Org. Lett. 202022, 3519-3523.

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    (7) Rh(I)/Bisoxazolinephosphine-Catalyzed Regio- and Enantioselective Allylic Substitutions

    Wen-Bin Xu, Samir Ghorai, Wenyu Huang, Changkun Li.*

    ACS. Catal202010, 4491-4496. 


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    (6)  Pd-Catalyzed Enantioselective Synthesis of 2-Methyl-3-methyleneindoline. 

    Chun-Hua Lu, Sima, Darvishi, Vahid, Khakyzadeh, Changkun Li.*

    Chin. Chem. Lett. 202031, doi.org/10.1016/j.cclet.2020.02.056. 




    (5) Cobalt-Catalyzed gem-Cross-Dimerization of Terminal Alkynes.

    Jia-Feng Chen, Changkun Li.*

    ACS. Catal. 202010, 3881-3889. 


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    (4) Cobalt-Catalyzed Regio- and Enantioselective Allylic Amination.

    Samir Ghorai, Sahadev Shrihari Chirke, Wen-Bin Xu, Jia-Feng Chen, Changkun Li.*

    J. Am. Chem. Soc. 2019141, 11430−11434.

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    (3) Construction of Vicinal Quaternary Carbon Centers via Cobalt-Catalyzed  Asymmetric Reverse Prenylation.

    Minghe Sun#, Jia-Feng Chen#, Shufeng Chen, Changkun Li.*

    Org. Lett. 201921, 1278-1281. (#, equal contribution)

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    (2) Enol Ester Synthesis via Cobalt-Catalyzed Regio- and Stereoselective

    Addition of Carboxylic Acids to Alkynes.

    Jia-Feng Chen, Changkun Li.*

    Org. Lett. 2018, 20, 6719-6724.

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    (1)  Rh(I)-Catalyzed Carbonylative [3+1] Constrcution of Cyclobutenones

    via C-C s-Bond Activation of Cyclopropenes.

    Wen-Bin Xu, Changkun Li,* and Jianbo Wang

    Chem. Eur. J. 2018, 24, 15786-15790.

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    2016年之前:

    (1) Rhodium-Catalyzed Chemo-, Regio-, and Enantioselective Addition of 2-Pyridones to Terminal Allenes
    Changkun Li, Matthias Kähny and Bernhard Breit* Angew. Chem., Int. Ed. 2014, 53, 13780-13784.
    (2) Rhodium-Catalyzed Chemo- and Regioselective Decarboxylative Addition of β-Ketoacids to Allenes: Efficient Construction of Tertiary and Quaternary Carbon Centers.
    Changkun Li, and Bernhard Breit* J. Am. Chem. Soc. 2014, 136, 862-865.
    (3) Pyridine-Directed Palladium-Catalyzed Phosphonation of C(sp2)-H Bonds
    Changkun Li, Takaaki Yano, Naoki Ishida, and Masahiro Murakami* Angew. Chem., Int. Ed. 2013, 52, 9801-9804.
    (4) Gold(I)-Catalyzed Cycloisomerization of Enynes Containing Cyclopropenes
    Changkun Li, Yi Zeng, Hang Zhang, Jiajie Feng, Yan Zhang, Jianbo Wang* Angew. Chem., Int. Ed. 2010, 49, 6413-6417.


  • 荣誉奖励

    2020 Thieme Chemistry Journal Award

    2016 入选中组部国家高层次海外人才计划青年项目

    2013 德国洪堡基金会奖学金
    2011 日本学术振兴会(JSPS)奖学金 

地址:上海市东川路800号 200240
电话:021-54742893
E-mail:sjtuscce@sjtu.edu.cn

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