2005年9月-2009年6月：武汉大学，药学院，药学，学士
2010年9月-2012年6月：武汉大学，药学院，药物化学，硕士 （导师：洪学传  教授）
2012年9月-2016年11月：华东师范大学，化学与分子工程学院，有机化学，博士 （导师：张俊良  教授）

2017年3月-2017年5月：上海润诺生物科技有限公司，有机合成高级研究员
2017年6月-2021年3月：湖南科技学院，制药工程系，讲师
2021年4月至今：上海交通大学化学化工学院，助理研究员

1）核苷的化学修饰与应用
2）化学生物学

1．湖南省自然科学基金青年基金，2018JJ3195，已结题

2．国家自然科学基金青年基金，21801075，已结题

3．上海交通大学医工交叉研究基金，YG2022QN019，在研

(1) Qin Zhao#, Ruoqian Xie#, Yuxiao Zeng, Wanlu Li, Guolan Xiao, Yangyan Li*, Gang Chen*, Palladium-catalyzed C–H Olefination of Uridine, Deoxyuridine, Uridine Monophosphate and Uridine Analogues, RSC Advances, 2022, 12, 24930.

 (2) Yuhua Ge*, Xingyue Chen, Yi Dong, Hua-Nan Wang, Yangyan Li, Gang Chen*, Access to benzene-modified 2^nd generation strigolactams and GR24 by merging C-H olefination with decarboxylative Giese cyclization, Org. Biomol. Chem., 2021, 19, 7141. 

(3) Yangyan Li#, Le Tu#, Xin Ma, Huan Chen, Yifan Fan, Qiang Zhou, Yao Sun*, Engineering a Smart Nanofluidic Sensor for High-performance Peroxynitrite Sensing Through a Spirocyclic Ring Open/Close Reaction Strategy, ACS Sens., 2021, 6, 3, 808.

(4)  Qingying Ouyang, Le Tu, Yi Zhang, Huan Chen, Yifan Fan, Yingfeng Tu*, Yangyan Li*, and Yao Sun*, Construction of a Smart Nanofluidic Sensor through a Redox Reaction Strategy for High-Performance Carbon Monoxide Sensing, Anal. Chem., 2020, 92, 14947. 

(5)  Xinsheng Xiao*, Sanping Huang, Shanshan Tang, Guokai Jia, Guangchuan Ou and Yangyan Li*, Ligand-free, Quinoline N-assisted Copper-catalyzed Nitrene Transfer Reaction to Synthesize 8-quinolylsulfimides, J. Org. Chem., 2019, 84, 7618.

(6)  Qingwen Gui, Kang Han, Zhuoliang Liu, Zhaohong Su, Xiaoli He, Hongmei Jiang*, Bufan Tian and Yangyan Li*, E-Selective synthesis of vinyl sulfones via silver-catalyzed sulfonylation of styrenes, Org. Biomol. Chem., 2018, 16, 5748. 

(7) Yangyan Li, Xiang Chen, Xiaoming Chen and Xiao Shen*, Organophosphine-Catalyzed [4C+X] Annulations, Molecules, 2018, 23, 3022. 

(8) Yangyan Li, Chao-Ze Zhu, Junliang Zhang*, Gold-Catalyzed [4+3] Cycloaddition/C–H Functionalization Cascade: Regio- and Diastereoselective Route to Cyclohepta[b]indoles. Eur. J. Org. Chem., 2017, 6609. 

(9) Yangyan Li, WenboLi, Junliang Zhang*, Gold-Catalyzed Enantioselective Annulations. Chem. Eur. J., 2017, 23, 467.

(10) Yangyan Li, Xiao Su, Wei Zhou, Wenbo Li, Junliang Zhang*, Amino Acid Derived Phosphine-Catalyzed Enantioselective 1,4-Dipolar Spiroannulation of Cyclobutenones and Isatylidenemalononitrile. Chem. Eur. J., 2015, 21, 4224.  

(11) Xiao Su#, Wei Zhou#, Yangyan Li, Junliang Zhang*, Design, Synthesis, and Application of a Chiral Sulfinamide Phosphine Catalyst for the Enantioselective Intramolecular Rauhut-Currier Reaction. Angew. Chem. Int. Ed., 2015, 54, 6874.

(12) Maomao He, Chunrong Qu, Bingbing Ding, Hao Chen, Yangyan Li, Guofu Qiu, Xianming Hu, Xuechuan Hong*, Total Synthesis of (±)-8-Oxo-erythrinine, (±)-8-Oxo-erythraline, and (±)-Clivonine, Eur. J. Org. Chem., 2015, 15, 3240. 

(13) Hao Chen, Maomao He, Yaya Wang, Linhui Zhai, Yongbo Cui, Yangyan Li, Yan Li, Haibing Zhou*, Xuechuan Hong*, Zixin Deng, Metal-free direct amidation of peptidyl thiol esters with α-amino acid esters. Green Chem., 2011, 13, 2723.

(1) 张俊良，宿晓，周伟，李杨燕. 一种手性叔膦化合物及其全构型、制备方法和应用[P]. 中国专利：CN104817591A, 2015-08-05。

(2)  肖新生，李杨燕，欧光川，唐珊珊，刘芳，权婷，黄三萍. S-烷基-S-喹啉基-N-磺酰基氮硫叶立德化合物及其制备和应用[P]. 中国专利：CN109810056B, 2020-09-29。