Zengming SHENProfessor

Tel: 021-54748325 
Email: shenzengming@sjtu.edu.cn 
Address: 上海市闵行区东川路800号上海交通大学建工楼312室 

Educational Background

Graduate ResearchAssistant,Shanghai Institute of Organic Chemistry(Sep.2001-July 2006)

Prof.Xiyan Lu, advisor

1. studied enantioselective hydrogenation of exocyclic double bond and its applications.

2. developed palladium(II)-catalyzed tandem intramolecular aminopalladation.

3. studiedCuX2-mediated intramolecular halocyclization reaction

Postdoctoral Fellow,University of Toronto(September2006-September 2008)

Prof.Vy M. Dong, advisor

1. developnew ways to functionalize carbon-hydrogen bonds.

2. Special-Research Professor,Shanghai Normal University(October2008-April 2010)

To be a Professor, Shanghai Jiao Tong University

study Cu-catalyzed C-C and C-H bond functionalization. We have achievedexploratorydevelopment and creative results (Please see the research and teaching statement for details).

Work Experience

1997-2001,Sichuan NormalUniversity, Bachelor

2001-2006,Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Organic Chemistry, September 2001-July 2006, Advisor:Prof. Xiyan Lu,  Ph.D.

2006-2008,University of Toronto (Canada), Advisor:Prof. Vy M. Dong,  Postdoctoral Fellow

2008-2010,Shanghai Normal University,  Professor

2010-2018.1 Shanghai Jiao Tong University,  Associate Professor

2018.1-        Shanghai Jiao Tong University,  Professor

Research Interests

1. 金属催化的C-C键和C-H键的活化

2. 金属催化的不对称反应的研究

3. 杂环化合物的研究,应用于药物和天然产物的合成

Research Project

1. “Design and synthesis of novel cyanating sources toward the application in cyanation reactions”,Fund from National Natural Science Foundation of China(21672144), 2017.01-2020.12.(650,000 yuan)

2. "Cu-catalyzed C-C bond cleavage”,Fund from National Natural Science Foundation of China(21272001),2013.1-2016.12.(800,000 yuan)

3. “Cu-catalyzed Cross-coupling Reaction via C-H bond activation”,Young Scientists Fund from National Natural Science Foundation of China(20902058),2010.01-2012.12. (190,000 yuan)

4. “Cu-catalyzed C-H bond functionalization”,Director Fund from National Natural Science Foundation of China(20852004), 2009.01-2012.12. (100,000 yuan)

5. Shanghai PujiangTalentProgram(09PJ1408100),2009.7-2011.7.(200,000 yuan)

6. “Cu-catalyzed C-C bond cleavage”,Shanghai Education Commission Innovation Key projects(13ZZ014),2013.1-2015.12.(160,000 yuan)

7.  “SMC-Young Scholar Fund” Excellent Young Teacher at Shanghai Jiao Tong University in 2010(B)”(200,000 yuan)

8. “Inert C-H bond Functionalization catalyzed by cheap metals”,Present Special Fund from Shanghai Jiao Tong University, 2011.1-2013.12.(300,000 yuan)


1.  Li, Xiaomeng; Guo, Yunlong; Shen, Zengming* J. Org. Chem. 2018, 83, 2818.

2. Cruz, Faben A.+; Zhu, Yamin+ (Contributed equally to this work); Tercenio, Quentin D.;Shen, Zengming*,Dong, Vy M.* “Alkyne Hydroheteroarylation: nantioselective Coupling of Indolesand Alkynes via Rh-Hydride Catalysis” J. Am. Chem. Soc.2017, 139, 10641-10644.

3. Zhu, Yamin;Shen, Zengming*“Copper-Catalyzed Acyloxycyanation of Alkynes with Acetonitrile: Regioselective Construction of Cyclic Acrylonitriles by 6-endo or 5-exo Cyclization”Adv. Synth. Catal. 2017,359, 3515.

4. Lu, Wenkui; Xu Hui;Shen Zengming* “Copper-catalyzed aromatic C–H alkoxylation with alcohols under aerobic conditions”Org. Biomol. Chem.,2017,15, 1261–1267.

5. Yu, Zhengwei; Li, Linyi;Shen, Zengming*“Cu-Catalyzed Cyanation of Aryl Iodides with Acetonitrile as Cyano Source”Chin. J. Org. Chem.2017,37, 1273-1277.

6. Zhang Wei; Yang, Shiping;Shen, Zengming* “Copper-Catalyzed Cyanomethylation of Substituted Tetrahydroisoquinolines with Acetonitrile”Adv. Synth. Catal.2016,358, 2392 – 2397.

7. Zhao, Mengdi; Zhang, Wei;Shen, Zengming* “Cu-Catalyzed Cyanation of Indoles with Acetonitrile as a Cyano source” J. Org. Chem.2015,80, 8868.

8. Li, Linyi; Yu, Zhengwei;Shen, Zengming*; “Copper-Catalyzed Aminoxylation of Different Types of Hydrocarbons with TEMPO: A Concise Route to N-Alkoxyamine Derivatives” Adv. Syn. Cat.2015, 357, 3495.

9. Zhu, Yamin; Li, Linyi;Shen, Zengming*“Cu-Catalyzed Cyanation of Arylboronic Acids with Acetonitrile: A Dual Role of TEMPO” Chem. Eur. J.2015,21, 13246.(Highlighted as a cover.)

10. Zhu, Yamin; Zhao, Mengdi; Lu, Wenkui; Li, Linyi;Shen, Zengming*“Acetonitrile as a Cyanating Reagent: Cu-Catalyzed Cyanation of Arenes” Org. Lett.2015,17, 2602. (Highlighted by Synform. See:Synform 2015, 10, A144–A145.)

11. Xu, Hui; Qiao, Xixue; Yang, Shiping;Shen, Zengming*“Cu-Catalyzed Direct Amidation of Aromatic C−H Bonds: An Access to Arylamines” J. Org. Chem.2014,79, 4414.

12. Kou, Xuezhen; Zhao, Mengdi; Qiao, Xixue; Zhu, Yamin; Tong, Xiaofeng;Shen, Zengming*“Copper-Catalyzed Aromatic C-H Bond Cyanation by C-CN Bond Cleavage of Inert Acetonitrile” Chem. Eur. J. 2013, 19, 16880-16886. (Highlighted as a frontispiece.)

13. Mo Song, Zhu Yamin,Shen Zengmging*,“Copper-catalyzed aromatic C–H bond halogenation with lithium halides under aerobic conditions” Org. Biomol. Chem.2013,11, 2756-2760. (Hot Paper, highlighted as a cover.)

14. Kou Xuezhen, Fan Jiajun, Tong Xiaofeng,Shen Zengming*,“Recent Progress in the Research of Transition Metal-Catalyzed C-CN Bond Cleavage” Chin. J. Org. Chem.2013,33, 1407-1422.

15. Shen, Zengming*;Ni, Zhenjie; Mo, Song; Wang, Jing; Zhu, Yamin; “Palladium-Catalyzed Intramolecular Decarboxylative Coupling of Arene Carboxylic Acids/Esters with Aryl Bromides” Chem. Eur. J. 2012,18, 4859-4865.

16. Wang,Ruiping; Mo, Song; Lu, Yongzhong;Shen, Zengming*; “Domino Sonogashira Coupling/Cyclization Reaction Catalyzed by Copper and ppb Levels of Palladium: A Concise Route to Indoles and Benzo[b]furans” Adv. Synth. Catal. 2011,353, 713-718.

17. Lu,Yongzhong; Wang,Ruiping;Qiao,Xixue;Shen, Zengming*;“Copper-Catalyzed Aromatic C–H Bond Halogenation Using Lithium Halides as Halogenating Reagents” Synlett, 2011,1038. ( the special issue of Synlett dedicated to Professors Xiyan Lu and Li-Xin Dai).

18. Shen, Zengming; Dornan, Peter K.; Khan, Hasan A; Woo, Tom; Dong, Vy M.“Mechanistic Insights into the Rhodium-Catalyzed Intramolecular Ketone Hydroacylation” J. Am. Chem. Soc.2009,131, 1077-1091.

19. Shen, Zengming; Dong, Vy M. “Benzofurans Prepared by C-H Bond Functionalization with Acylsilanes” Angew. Chem. Int. Ed.2009,48, 784-786. (For a highlight, see: Synfacts, 2009, 4, 409).

20. Shen, Zengming; Khan, Hasan A.; Dong, Vy M.“Rh-Catalyzed Carbonyl Hydroacylation: An Enantioselective Approach to Lactones” J. Am. Chem. Soc.2008,130, 2916-2917. • (See the highlight in Chemistry World featuring this work: James Mitchell Crow, "Rhodium fast tracks route to lactones." Editorial Board of SYNFACTS selects this article as the Synfact of the month, see: Synfacts, 2008, 5, 485).

21. Shen, Zengming; Lu, Xiyan; “Cupric Halide-Mediated Intramolecular Halocyclization ofN-Electron-Withdrawing Group-Substituted 2-Alkynylanilines for the Synthesis of 3-Haloindoles” Adv. Synth. Catal.2009,351, 3107-3112.



1.  Undergraduate course:《Organic Chemistry》:332(course times); Teaching 2010,2013-2017 grades.

2. Graduate course:《Modern Organic Chemistry》:252(course times); Teaching 2010-2017 grades.

3. Ph.D.Graduate course:《Lecture》:18(course times); Teaching 2011-2017 grades.

Honors and Awards

1. Excellent Graduate at the ChineseAcademyof Sciences (2006) (Three students were awarded this honor every year throughout the Shanghai Institute of Organic Chemistry).

2. Shanghai PujiangTalentProgram(2009)

Ÿ3.  “SMC-Young ScholarFund” Excellent Young Teacher at the Shanghai Jiao Tong University in 2010(B)

Ÿ4.  “March 8 red-banner pacesetter at Shanghai JiaoTong University”during 2013-2014

Ÿ5. Won theFirstPrize in the First Young Teachers Teaching Competition at Shanghai Jiao Tong University in 2016.

6.Ÿ  Shanghai Jiao Tong University Teaching Experts Award(2016)

Ÿ7. Won theSecondPrize in the Second ShanghaiUniversitiesTeaching Competition for Young Teachers in 2016.

Address:800 Dongchuan RD. Minhang District, Shanghai, China
PostCode:200240 Tel:021-54742893 E-mail:sjtuscce@sjtu.edu.cn


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